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Table 4 Association of urinary proteins with renal histological lesions

From: Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis

 

Odds ratio

95 % CI

P*

Mesangial cellularity

   

u IgG (mg/g uCr)

2.86

1.36‒6.03

.006

u Albumin (mg/g uCr)

3.57

1.80‒7.07

.000

u Transferrin (mg/g uCr)

2.90

1.64‒5.12

.000

u α1‒microglobulin (mg/g uCr)

2.85

1.13‒7.21

.027

24‒h Proteinuria (mg/m2/h)

2.79

1.15‒6.81

.024

Glomerulosclerosis

   

u Transferrin (mg/g uCr)

1.86

1.03‒3.36

.038

24‒h Proteinuria (mg/m2/h)

5.16

1.37‒19.43

.015

Tubule‒interstitial damage

   

u Transferrin (mg/g uCr)

1.89

1.01‒3.54

.048

u NAG (mg/g uCr)

45.39

2.10‒980

.015

  1. The level of urinary proteins was log‒transformed due to a skewed distribution
  2. Odds ratio represents the increase in odds per log increase in the level of urinary proteins.
  3. * The association remained significant after adjustment for potential confounders, including age, clinical features, histological diagnosis or treatment with prednisone and cyclophosphamide.
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BMC Nephrology

ISSN: 1471-2369

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