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Table 1 Demographic and clinical characteristics of the study population based on the increased mean IMT

From: Association between microalbuminuria and subclinical atherosclerosis evaluated by carotid artery intima-media in elderly patients with normal renal function

 

All(n = 272)

< 1.05 mm (n = 209)

≥ 1.05 mm (n = 63)

P value

Age (y)

70.2 ± 3.9

69.8 ± 3.6

71.2 ± 4.6

< 0.01

Male (%)

52.6

46.4

73.0

0.001

Current smoker (%)

33.8

29.7

47.6

< 0.01

Hypertension (%)

82.7

82.8

82.5

1.00

Diabetes (%)

37.9

36.4

42.9

0.38

SBP (mmHg)

138.2 ± 17.7

136.9 ± 17.9

142.6 ± 16.6

0.03

DBP (mmHg)

77.7 ± 10.3

77.6 ± 9.9

78.2 ± 11.4

0.68

PP (mmHg)

60.5 ± 14.1

59.3 ± 14.3

64.4 ± 12.7

0.01

BMI (kg/m2)

24.0 ± 2.5

24.4 ± 2.5

22.9 ± 2.3

< 0.001

Waist circumference (cm)

89.5 ± 9.2

88.8 ± 9.3

91.5 ± 8.7

0.04

Central obesity (%)

67.5

68.3

65.1

0.65

Total cholesterol (mmol/L)

5.17 ± 0.99

5.18 ± 1.00

5.15 ± 0.95

0.88

Triglycerides(mmol/L)

1.99 ± 1.41

1.93 ± 1.20

2.18 ± 1.96

0.21

HDL cholesterol (mmol/L)

1.36 ± 0.34

1.40 ± 0.35

1.24 ± 0.27

< 0.01

Hypercholesterolemia (%)

13.2

13.9

11.1

0.68

Hypertriglyceridemia (%)

49.6

48.3

54.0

0.47

Serum creatinine (mg/dL)

0.70 ± 0.13

0.69 ± 0.13

0.74 ± 0.14

0.03

eGFR (ml/min/1.73 m2)

91.1 ± 8.5

91.3 ± 8.7

90.4 ± 7.8

0.48

Serum uric acid (μmol/L)

305.3 ± 74.4

302.4 ± 74.5

314.8 ± 73.3

0.25

ACR (median,IQR)

3.1 (1.8-8.0)

3.1 (1.8-7.1)

3.0 (1.5-15.2)

0.46

Microalbuminuria (%)

12.5

9.6

22.2

0.02

Mean IMT (mm)

0.87 ± 0.30

0.74 ± 0.15

1.33 ± 0.22

< 0.001

Maximal IMT (mm)

1.64 ± 0.75

1.35 ± 0.54

2.60 ± 0.53

< 0.001

  1. Note: To convert serum cholesterol in mmol/L to mg/dL, multiply by 38.67; serum triglycerides in mmol/L to mg/dL, multiply by 88.545; serum creatinine in mg/dL to μmol/L, multiply by 88.4; serum uric acid in μmol/L to mg/dL, multiply by 0.01681. Central obesity was defined as a waist measurement greater than 90 cm for men or greater than 80 cm for women; Hypercholesterolemia was defined as total cholesterol greater than 240 mg/dL; Hypertriglyceridemia was defined as triglycerides greater than 150 mg/dL.
  2. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; BMI, body mass index; HDL, high-desity lipoprotein; eGFR, estimated glomerular filtration rate; ACR, albumin-creatinine ratio; IQR, interquartile range; IMT, intima-media thickness.