Skip to main content

Table 1 Baseline characteristics of 16,010 NHANES III (1988–1994) participants stratified by eGFR MDRD and eGFR CKD-EPI

From: Comparing the association of GFR estimated by the CKD-EPI and MDRD study equations and mortality: the third national health and nutrition examination survey (NHANES III)

EGFRMDRD

≥120

90-119

60-89

30-59

<30

(No. of participants)a

(2,729)

(6,604)

(5,606)

(1,015)

(56)

EGFRCKD-EPI

≥120

90-119

≥120

90-119

60-89

90-119

60-89

30-59

60-89

30-59

<30

<30

Number of participants a (%) b

2,416

312 d

1,473

4,969

162

1,870

3,664

72

120

883

12

55 e

(88.3)

(11.7)

(20.2)

(78.4)

(1.4)

(42.9)

(56.6)

(0.5)

(19.4)

(79.5)

(1.1)

(99.5)

Characteristic c

            

Serum Creatinine (mg/dl)

0.64

0.59

0.76

0.79

0.70

0.87

0.94

1.07

1.07

1.26

1.97

2.76

(0.004)

(0.01)

(0.003)

(0.002)

(0.01)

(0.004)

(0.004)

(0.03)

(0.02)

(0.02)

(0.11)

(0.20)

EGFRMDRD (ml/min/1.73 m2)

138

131

112

100

98

85

74

61

58

49

31

23

(0.63)

(0.72)

(0.17)

(0.18)

(0.28)

(0.09)

(0.13)

(0.09)

(0.13)

(0.27)

(0.32)

(0.88)

EGFRCKD-EPI (ml/min/1.73 m2)

133

112

124

109

87

96

79

59

63

50

29

22

(0.36)

(0.51)

(0.14)

(0.12)

(0.27)

(0.18)

(0.20)

(0.13)

(0.20)

(0.30)

(0.24)

(0.92)

Age (years)

26 (0.2)

53 (0.8)

28 (0.3)

39 (0.2)

79 (0.5)

40 (0.5)

59 (0.6)

83 (1.0)

56 (1.11)

72 (0.74)

81 (2.12)

72 (1.75)

Age < 65 years, N (%) a b

2,415

247

1,473

4,614

0

1,754

1,717

0

100

115

0

12

(99.9)

(85.8)

(100)

(96.4)

 

(95.8)

(61.3)

 

(83.8)

(18.0)

 

(16.9)

Male (%)

40

55

44

53

56

46

49

60

24

40

72

35

Race/Ethnicity (%)

            

Non-Hispanic White

52

67

65

74

85

86

86

86

90

86

90

73

Non-Hispanic Black

25

9

19

11

7

4

7

13

1

8

9

18

Mexican American

13

10

8

6

2

4

2

1

2

1

1

2

Other

11

13

9

10

7

6

6

1

6

5

0

8

Ever or Current Smoker (%)

45

68

46

56

47

51

54

43

57

55

84

56

Diabetes (%)

3

13

<1

3

11

3

8

6

14

15

27

26

Prior CVD (%)

<1

<1

<1

3

16

3

10

22

13

26

73

35

Body Mass Index (kg/m2)

25

27

25

26

25

26

27

25

29

28

25

26

(0.23)

(0.75)

(0.20)

(0.14)

(0.26)

(0.20)

(0.15)

(0.45)

(0.68)

(0.24)

(1.02)

(1.18)

Systolic Blood Pressure, mm Hg

112

130

112

119

145

118

131

143

130

143

150

145

(0.46)

(1.90)

(0.34)

(0.31)

(1.86)

(0.45)

(0.59)

(1.99)

(2.22)

(1.03)

(6.01)

(3.66)

Diastolic Blood Pressure, mm Hg

68

78

69

74

73

75

76

72

76

75

71

73

(0.41)

(0.95)

(0.35)

(0.28)

(1.05)

(0.32)

(0.25)

(1.14)

(0.85)

(0.49)

(2.11)

(2.98)

Antihypertensive medication use (%)

4

26

2

10

32

10

27

44

36

60

75

74

Total Cholesterol (mg/dl)

183

217

181

198

208

204

217

213

230

232

209

230

(1.69)

(4.92)

(1.68)

(1.14)

(3.82)

(1.57)

(1.21)

(5.49)

(4.65)

(2.81)

(10.31)

(14.24)

CRP (mg/dl; %)

            

<0.22

73

58

80

75

71

76

67

62

64

52

29

42

0.22-0.99

19

29

14

19

22

19

25

28

23

32

12

40

≥1.00

9

13

6

6

7

5

8

10

13

16

59

18

ACR (mg/g; %)

            

<30

93

84

93

94

74

95

89

78

83

70

9

34

30-300

6

11

7

5

25

5

10

18

15

23

68

20

≥300

<1

5

<1

<1

17

1

1

4

3

7

23

46

  1. Abbreviations: CVD, Cardiovascular Disease; eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CRP, C-reactive protein; ACR, albumin-to-creatinine ratio.
  2. Note: Conversion factors for units: low- and high-density lipoprotein cholesterol in mg/dL to mmol/L, ×0.02586; triglycerides in mg/dL to mmol/L, ×0.01129; creatinine in mg/dL to μmol/L, ×88.4; eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667; albumin-creatinine ratio in mg/g to mg/mmol, divide by 8.84.
  3. a Participant numbers are unweighted N.
  4. b Percent represents the population percent representative of the non-institutionalized US population; total may not equal 100% due to rounding.
  5. c Values presented are population % for categorical variables and mean (linearized standard error) for continuous variables.
  6. d One 86 year old Mexican-American female with serum creatinine = 0.488 mg/dL had eGFRMDRD = 120 ml/min/1.73 m2 and eGFRCKD-EPI 89 ml/min/1.73 m2 (data not shown).
  7. e One 64 year old Mexican-American female with serum creatinine = 1.736 had eGFRMDRD = 29.5 ml/min/1.73 m2 and eGFRCKD-EPI = 30.6 ml/min/1.73 m2 (data not shown).