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Table 1 Baseline characteristics of 16,010 NHANES III (1988–1994) participants stratified by eGFR MDRD and eGFR CKD-EPI

From: Comparing the association of GFR estimated by the CKD-EPI and MDRD study equations and mortality: the third national health and nutrition examination survey (NHANES III)

EGFRMDRD ≥120 90-119 60-89 30-59 <30
(No. of participants)a (2,729) (6,604) (5,606) (1,015) (56)
EGFRCKD-EPI ≥120 90-119 ≥120 90-119 60-89 90-119 60-89 30-59 60-89 30-59 <30 <30
Number of participants a (%) b 2,416 312 d 1,473 4,969 162 1,870 3,664 72 120 883 12 55 e
(88.3) (11.7) (20.2) (78.4) (1.4) (42.9) (56.6) (0.5) (19.4) (79.5) (1.1) (99.5)
Characteristic c             
Serum Creatinine (mg/dl) 0.64 0.59 0.76 0.79 0.70 0.87 0.94 1.07 1.07 1.26 1.97 2.76
(0.004) (0.01) (0.003) (0.002) (0.01) (0.004) (0.004) (0.03) (0.02) (0.02) (0.11) (0.20)
EGFRMDRD (ml/min/1.73 m2) 138 131 112 100 98 85 74 61 58 49 31 23
(0.63) (0.72) (0.17) (0.18) (0.28) (0.09) (0.13) (0.09) (0.13) (0.27) (0.32) (0.88)
EGFRCKD-EPI (ml/min/1.73 m2) 133 112 124 109 87 96 79 59 63 50 29 22
(0.36) (0.51) (0.14) (0.12) (0.27) (0.18) (0.20) (0.13) (0.20) (0.30) (0.24) (0.92)
Age (years) 26 (0.2) 53 (0.8) 28 (0.3) 39 (0.2) 79 (0.5) 40 (0.5) 59 (0.6) 83 (1.0) 56 (1.11) 72 (0.74) 81 (2.12) 72 (1.75)
Age < 65 years, N (%) a b 2,415 247 1,473 4,614 0 1,754 1,717 0 100 115 0 12
(99.9) (85.8) (100) (96.4)   (95.8) (61.3)   (83.8) (18.0)   (16.9)
Male (%) 40 55 44 53 56 46 49 60 24 40 72 35
Race/Ethnicity (%)             
Non-Hispanic White 52 67 65 74 85 86 86 86 90 86 90 73
Non-Hispanic Black 25 9 19 11 7 4 7 13 1 8 9 18
Mexican American 13 10 8 6 2 4 2 1 2 1 1 2
Other 11 13 9 10 7 6 6 1 6 5 0 8
Ever or Current Smoker (%) 45 68 46 56 47 51 54 43 57 55 84 56
Diabetes (%) 3 13 <1 3 11 3 8 6 14 15 27 26
Prior CVD (%) <1 <1 <1 3 16 3 10 22 13 26 73 35
Body Mass Index (kg/m2) 25 27 25 26 25 26 27 25 29 28 25 26
(0.23) (0.75) (0.20) (0.14) (0.26) (0.20) (0.15) (0.45) (0.68) (0.24) (1.02) (1.18)
Systolic Blood Pressure, mm Hg 112 130 112 119 145 118 131 143 130 143 150 145
(0.46) (1.90) (0.34) (0.31) (1.86) (0.45) (0.59) (1.99) (2.22) (1.03) (6.01) (3.66)
Diastolic Blood Pressure, mm Hg 68 78 69 74 73 75 76 72 76 75 71 73
(0.41) (0.95) (0.35) (0.28) (1.05) (0.32) (0.25) (1.14) (0.85) (0.49) (2.11) (2.98)
Antihypertensive medication use (%) 4 26 2 10 32 10 27 44 36 60 75 74
Total Cholesterol (mg/dl) 183 217 181 198 208 204 217 213 230 232 209 230
(1.69) (4.92) (1.68) (1.14) (3.82) (1.57) (1.21) (5.49) (4.65) (2.81) (10.31) (14.24)
CRP (mg/dl; %)             
<0.22 73 58 80 75 71 76 67 62 64 52 29 42
0.22-0.99 19 29 14 19 22 19 25 28 23 32 12 40
≥1.00 9 13 6 6 7 5 8 10 13 16 59 18
ACR (mg/g; %)             
<30 93 84 93 94 74 95 89 78 83 70 9 34
30-300 6 11 7 5 25 5 10 18 15 23 68 20
≥300 <1 5 <1 <1 17 1 1 4 3 7 23 46
  1. Abbreviations: CVD, Cardiovascular Disease; eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CRP, C-reactive protein; ACR, albumin-to-creatinine ratio.
  2. Note: Conversion factors for units: low- and high-density lipoprotein cholesterol in mg/dL to mmol/L, ×0.02586; triglycerides in mg/dL to mmol/L, ×0.01129; creatinine in mg/dL to μmol/L, ×88.4; eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667; albumin-creatinine ratio in mg/g to mg/mmol, divide by 8.84.
  3. a Participant numbers are unweighted N.
  4. b Percent represents the population percent representative of the non-institutionalized US population; total may not equal 100% due to rounding.
  5. c Values presented are population % for categorical variables and mean (linearized standard error) for continuous variables.
  6. d One 86 year old Mexican-American female with serum creatinine = 0.488 mg/dL had eGFRMDRD = 120 ml/min/1.73 m2 and eGFRCKD-EPI 89 ml/min/1.73 m2 (data not shown).
  7. e One 64 year old Mexican-American female with serum creatinine = 1.736 had eGFRMDRD = 29.5 ml/min/1.73 m2 and eGFRCKD-EPI = 30.6 ml/min/1.73 m2 (data not shown).