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Table 2 Adjusted a hazard ratio (95% Confidence interval) of all-Cause and cardiovascular disease mortality, by eGFR categories among 16,010 participants of NHANES III (1988–1994) with follow-up till December 31, 2006

From: Comparing the association of GFR estimated by the CKD-EPI and MDRD study equations and mortality: the third national health and nutrition examination survey (NHANES III)

  

Categories of eGFR (ml/min/1.73 m2)

  

≥ 120

90-119

60-89

30-59

< 30

All-Cause Mortality

      

EGFR CKD-EPI

Participants, N

3,889

7,151

3,947

956

67

 

Deaths, N

179

921

1,686

775

59

 

HR

2.05

Reference

0.97

1.39

1.38

 

(95% CI)

(1.55-2.71)

 

(0.86-1.10)

(1.17-1.65)

(0.88-2.16)

EGFR MDRD

Participants, N

2,729

6,604

5,606

1,015

56

 

Deaths, N

228

805

1,788

750

49

 

HR

1.70

Reference

0.94

1.31

1.96

 

(95% CI)

(1.36-2.14)

 

(0.84-1.05)

(1.11-1.56)

(1.11-3.44)

CVD Mortality

      

EGFR CKD-EPI

Participants, N

3,889

7,151

3,947

956

67

 

Deaths, N

41

303

755

412

29

 

HR

2.70

Reference

1.05

1.49

1.64

 

(95% CI)

(1.54-4.73)

 

(0.87-1.26)

(1.16-1.92)

(1.02-2.65)

EGFR MDRD

Participants, N

2,729

6,604

5,606

1,015

56

 

Deaths, N

64

278

774

401

23

 

HR

1.53

Reference

0.95

1.32

2.17

 

(95% CI)

(0.96-2.45)

 

(0.79-1.13)

(0.99-1.78)

(1.18-3.98)

  1. Abbreviations: eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CVD, Cardiovascular Disease.
  2. a Adjusted for age, sex, race/ethnicity, prior CVD, diabetes, smoking, systolic and diastolic blood pressure, use of antihypertensive medications, body mass index, cholesterol, C-reactive protein category and albumin-to-creatinine ratio category.
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BMC Nephrology

ISSN: 1471-2369

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