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Table 4 Net reclassification improvement by the CKD-EPI equation among participants with eGFR <120 ml/min/1.73 m 2 by both equations stratified by age, sex and race

From: Comparing the association of GFR estimated by the CKD-EPI and MDRD study equations and mortality: the third national health and nutrition examination survey (NHANES III)

  Reclassification, number (Population %)a Deaths, NRI
   All-cause (CVD) All-cause CVD
Overall 11,808 (24.1%) 3,339 (1,463) 0.2073*** 0.2216***
By Age Categories
17-44 4,822 (30.3%) 208 (58) 0.0216 −0.0883
45-64 3,491 (21.8%) 715 (258) −0.0146 −0.0006
≥65 3,495 (11.4%) 2,416 (1,147) 0.1362*** 0.0943***
By Sex
Male 5,839 (22.1%) 1,844 (796) 0.2077*** 0.2277***
Females 5,969 (26.0%) 1,495 (667) 0.2063*** 0.2157***
By Race/Ethnicity
NH Whites 5,736 (25.7%) 1,957 (903) 0.2258*** 0.2368***
NH Blacks 2,701 (12.8%) 710 (290) 0.1245*** 0.1229***
Mex-Am 2,868 (20.2%) 594 (239) 0.0648** 0.0682*
Others 503 (20.2%) 78 (31) 0.1427* 0.2559*** b
  1. Abbreviations: eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; NRI, Net Reclassification Improvement; NH, Non-Hispanic; Mex-Am, Mexican-American.
  2. a Reclassification to a different eGFR category by CKD-EPI equation. Number represents the number of participants; Population % is representative of the non-institutionalized US population.
  3. b NRI estimates less precise as there are <50 events in this cell.
  4. * p < 0.05; ** p < 0.01; *** p < 0.001.