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Table 4 Prevalence of renal dysfunction in 37 patients with ACL before and after specific treatment

From: Renal function evaluation in patients with American Cutaneous Leishmaniasis after specific treatment with pentavalent antimonial

 

Pre-treatment

Post-treatment

P

P creat >1.2 mg/dl

-

-

-

CrCl <90 ml/min/1.73 m 2

11 (30%)

12 (32%)

1.000

Microalbuminuria > 30 mg/g creat

12 (39%)

3 (10%)

0.004

U osm T4 < 700mmOsm/kg H 2 O

21 (62%)

24 (71%)

0.508

U/P osm T4 < 2.8

26 (77%)

30 (88%)

0.344

U pH T4 > 5.5

15 (40%)

6 (16%)

0.012

EF Na+ > 2%

5 (14%)

4 (11%)

1.000

EF k+ > 10%

12 (32%)

11(30%)

1.000

EF Ca++ > 3%

2 (5%)

2 ( 5%)

1.000

EF PO4- > 10%

17 (46%)

10 (27%)

0.143

EF Mg++ > 6%

1 (2.7%)

1 (2.7%)

1.000

  1. Pcrea – plasma creatinine; CrCl – creatinine clearance; U/Posm – urine and plasma osmolarity ratio; UpH T4 – urine pH in T4 (4 hours after CaCl2 administration); Uosm T4 – urine osmolariry in T4 (4 hours after DDAVP administration); EFNa – Sodium excretion fraction; EFK – Potassium excretion fraction; EFCa – Calcium excretion fraction; EFMg – Magnesium excretion fraction. Data expressed as percentage (%).