Skip to main content

Table 2 The number of antihypertensive agents used in the patients with hypertension and diabetes at the baseline and at the endpoint of the observation

From: Hypertension resistant to antihypertensive agents commonly occurs with the progression of diabetic nephropathy in Japanese patients with type 2 diabetes mellitus: a prospective observational study

  Albuminuria stage  
  A1 A2 A3 Average
GFR stage Baseline$ Endpoint$ Baseline$ Endpoint$ Baseline$ Endpoint$ Baseline$ Endpoint$
G1 + G2 1.3 ± 1.0 1.7 ± 1.0 1.1 ± 1.0 1.7 ± 1.0 1.2 ± 0.8 2.0 ± 0.9 1.2 ± 1.0 1.7 ± 1.0
n (% of all) 261 (18.3) 182 (18.4) 127 (8.9) 79 (8.0) 58 (4.1) 37 (3.7) 446 (31.4) 298 (40)
G3a# 1.4 ± 1.0 1.7 ± 1.0 1.4 ± 1.1 1.8 ± 1.2 1.5 ± 0.9 2.3 ± 1.2 1.4 ± 1.0 1.8 ± 1.1
n (% of all) 269 (18.9) 217 (21.9) 140 (9.9) 82 (8.3) 86 (6.1) 68 (6.9) 495 (34.9) 367 (37.1)
G3b# 1.9 ± 1.1 2.1 ± 1.2 1.5 ± 1.3 2.0 ± 1.1 2.0 ± 1.3 2.6 ± 1.4 1.9 ± 1.3 2.3 ± 1.3*
n (% of all) 123 (8.7) 93 (9.4) 63 (4.4) 40 (4.0) 106 (7.5) 79 (8.0) 292 (20.6) 212 (21.4)
G4 + G5 3.0 ± 1.6 3.2 ± 1.8 2.4 ± 1.6 2.6 ± 1.2 2.5 ± 1.3 2.9 ± 1.4 2.5 ± 1.4 2.9 ± 1.4
n (% of all) 10 (1.0) 6 (0.9) 22 (1.5) 8 (0.8) 155 (10.9) 99 (10) 187 (13.2) 113 (11.4)
Average*# 1.5 ± 1.1 1.8 ± 1.1 1.4 ± 1.2 1.8 ± 1.1 2.0 ± 1.3 2.5 ± 1.4 1.6 ± 1.2 2.0 ± 1.3
n (% of all) 663 (46.7) 498 (50.3) 352 (24.8) 209 (21.1) 405 (28.5) 283 (28.6) 1420 (100) 990 (100)
  1. * P < 0.01 among A1, A2 and A3 at baseline and # P < 0.01 among A1, A2 and A3 at endpoint.
  2. $ P < 0.01 among G1 + G2, G2, G3 and G4 + G5.