Figure 4

Pharmacokinetic evaluation (PK-A population; n = 12) at baseline (V2) and 4 weeks (V3). The first sample was obtained after 1 minute, resulting in a high peak compared to other studies in which first samples were obtained later. Legend: values at 24 and 48 h not displayed (0.01-0.02). In a number of patients these values were below the detection limit of the assay. Means are displayed in red and 95% confidence intervals in blue.