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Table 3 Associations of 25(OH)D levels and severity of albuminuria and Impaired eGFR

From: 25-hydroxyvitamin D Levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study

 

25(OH)D < 50 nmol/L, OR (95% CI)

 

Model 1a

p

Model 2b

p

Model 3c

p

No Albuminuria

Ref

 

Ref

 

Ref

 

Micro-albuminuria

2.06 (1.51-2.82)

<0.001

1.80 (1.35-2.41)

<0.001

1.59 (1.15-2.21)

0.007

Macro-albuminuria

1.99 (0.95-4.17)

0.07

1.70 (0.92-3.13)

0.09

1.22 (0.76-1.98)

0.39

 

25(OH)D < 50 nmol/L, OR (95% CI)

 

Model 1 a

 

Model 2 b

 

Model 3 d

 

eGFR ≥60

Ref

 

Ref

 

Ref

 

eGFR 30-59

1.25 (0.78-2.02)

0.34

0.79 (0.53-1.16)

0.22

0.84 (0.56-1.26)

0.39

eGFR <30

9.31 (2.11-41.1)

0.004

5.93 (1.20-29.2)

0.03

4.46 (0.88-22.7)

0.07

  1. CI – confidence interval, OR – odds ratio.
  2. a unadjusted.
  3. b adjusted for age and gender.
  4. c adjusted for age, gender, diabetes, body mass index, triglycerides, cardiovascular disease, smoking, season, glomerular filtration rate and systolic blood pressure.
  5. d adjusted for age, gender, diabetes, cholesterol, triglycerides, body mass index, smoking, ethnicity, cardiovascular disease, albuminuria and systolic blood pressure.
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BMC Nephrology

ISSN: 1471-2369

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