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Table 3 Hazard Ratios (HRs) for incident CVD in 6,209 participants at baseline by CKD a and BMI b categories

From: “Association between moderate renal insufficiency and cardiovascular events in a general population: Tehran lipid and glucose study”

 

Without CKDa

  

With CKD

  

Variables

BMI 18.5-24.9 (N = 1398)

BMI 25–29.9 (N = 2314)

BMI ≥ 30 (N = 1548)

BMI 18.5-24.9 (N = 379)

BMI 25–29.9 (N = 418)

BMI ≥ 30 (N = 152)

No. of person-years

12329

17274

9936

2094

4748

3834

No. of incidence CVD

64

135

82

30

78

50

Incidence rate

52

78

82

143

164

130

(per 10,000 person-years)

Unadjusted HRs

1

1.52 (1.13-2.06)*

1.60 (1.15-2.23)*

2.94 (1.90-4.55)*

3.36 (2.41-4.67)*

2.64 (1.82-3.83)*

Adjusted HRs

Model 1†

1

1.65 (1.22-2.22)*

2.03 (1.45-2.83)*

1.45(0.92-2.27)

2.02 (1.42-2.85)*

2.11 (1.42-3.12)*

Model 2‡

1

1.24 (0.86-1.79)

1.12 (0.62-1.99)

1.41(0.90-2.22)

1.43 (0.95-2.15)

1.08 (0.59-1.99)

  1. a CKD status based on MDRD category.
  2. b Body mass index.
  3. †Model 1 was adjusted for age, sex.
  4. ‡Model 2, we further adjusted for, smoking (reference: no), history of diabetes mellitus (reference: no), family history of premature CAD (reference: no), Hyper TG (reference: TG < 150 mg/dl), Hyper TC (reference: TC < 240), hypertension (reference: SBP/DBP < 140/90 mmHg).
  5. *P < 0.05.
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BMC Nephrology

ISSN: 1471-2369

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