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Figure 2 | BMC Nephrology

Figure 2

From: UT-B-deficient mice develop renal dysfunction and structural damage

Figure 2

Effect of acute urea loading on the urinary concentrating ability and renal urea handling in 52-week-old UT-B-null and wild-type mice. An acute urea load (300 μmol) was injected intraperitoneally after the first 2-h urine collection (time 0). A: Urea excretion. B: Urinary output. C: Urinary urea concentration (Uurea). D: Urinary osmolality (Uosm). E: Excretion of non-urea solutes. F: Non-urea solute concentration (Unon-urea solutes). Two-way ANOVA (genotype and 2-h periods) indicated significant differences between the two genotypes at the indicated times (Fisher's post hoc test).

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