Table 5 Concordantly regulated SAGE transcripts from the ROP-Os/+ mouse model (as compared to C57-Os) and transcripts derived from microarray of human kidney biopsies from patients with FSGS (as compared to normal controls)
TAG count in ROP-Os | TAG count in C57-Os | Genes concordantly regulated between mouse model and human Glomerulus | log Fold Change | q-value | Genes concordantly regulated between mouse model and human tubuloninterstitium | log Fold Change | q- value |
|---|---|---|---|---|---|---|---|
0 | 7 | Slc 22a6 | −0.42 | 0.00 | Slc22a6 | −0.22 | 0.00 |
0 | 9 | Slc4a4 | −0.32 | 0.00 |  |  |  |
1.35 | 13 | Aqp1 | −0.30 | 0.00 |  |  |  |
5.4 | 0 | Psmb5 | 0.21 | 0.00 | Â | Â | Â |
5.4 | 0 | Pcbp1 | 0.24 | 0.00 | Â | Â | Â |
5.4 | 0 | Psma3 | 0.31 | 0.00 | Â | Â | Â |
6.75 | 20 | Pdzk1ip1 | −0.15 | 0.02 |  |  |  |
74.25 | 45 | Igfbp7 | 0.14 | 0.02 | Â | Â | Â |
12.15 | 3 | Mdh2 | 0.16 | 0.02 | Â | Â | Â |
9.45 | 0 | Vamp8 | 0.11 | 0.03 | Â | Â | Â |
8.1 | 1 | Tmbim4 | 0.12 | 0.03 | Â | Â | Â |
5.4 | 0 | Ndufb11 | 0.21 | 0.03 | Â | Â | Â |
4.05 | 16 | Lifr | −0.09 | 0.05 | Lifr | −0.27 | 0.00 |
12.15 | 3 | Sod1 | 0.06 | 0.09 | Â | Â | Â |
16.2 | 6 | Herpud1 | −0.07 | 0.14 |  |  |  |
2.7 | 13 | Atp6v1a | −0.03 | 0.15 |  |  |  |
8.1 | 42 | Nrp2b | −0.03 | 0.15 |  |  |  |
2.7 | 12 |  | 0.11 | 0.11 | Id2 | −0.40 | 0.00 |