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Table 2 Associations between ESRD and cancer risk

From: Cancer risk among elderly persons with end-stage renal disease: a population-based case–control study

 

N

ESRD

OR (95%CI)

P value

  

N

%

  

Controls

99,615

357

0.36

ref

--

Overall cancer

1,029,732

3582

0.35

1.02 (0.91, 1.14)

0.8

Specific cancer site:

     

 Tongue

4,007

18

0.45

1.32 (0.82, 2.13)

0.3

 Gum and other mouth

3,407

<11

<0.4

0.95 (0.50, 1.78)

0.9

 Esophagus

10,261

39

0.38

1.02 (0.73, 1.43)

0.9

 Stomach

20,106

118

0.59

1.45 (1.16, 1.81)

0.001*

 Small intestine

3,502

24

0.69

1.92 (1.27, 2.92)

0.002

 Colon

104,002

390

0.37

1.17 (1.00, 1.36)

0.05

 Rectum

33,086

91

0.28

0.82 (0.65, 1.04)

0.11

 Liver

9,034

63

0.70

1.53 (1.16, 2.01)

0.003

 Gallbladder

3,430

15

0.44

1.32 (0.78, 2.22)

0.3

 Other biliary

4,389

27

0.62

1.78 (1.20, 2.65)

0.004

 Pancreas

29,765

122

0.41

1.21 (0.98, 1.50)

0.07

 Larynx

7,431

33

0.44

1.15 (0.80, 1.66)

0.4

 Lung

161,687

661

0.41

1.17 (1.02, 1.34)

0.02

 Soft tissue (including heart)

4,202

<11

<0.4

0.56 (0.28, 1.12)

0.1

 Melanoma of skin

24,626

75

0.30

1.07 (0.82, 1.41)

0.6

 Other non-epithelial skin

3,585

17

0.47

1.58 (0.96, 2.59)

0.07

 Breast

122,315

339

0.28

1.11 (0.90, 1.38)

0.3

 Cervix

3,686

28

0.76

2.12 (1.39, 3.23)

<0.001*

 Uterine corpus

24,507

66

0.27

1.05 (0.77, 1.43)

0.8

 Ovary

14,683

40

0.27

1.07 (0.75, 1.54)

0.7

 Prostate

193,632

336

0.17

0.42 (0.35, 0.50)

<0.001*

 Bladder

55,559

218

0.39

1.20 (1.00, 1.44)

0.05

 Kidney and renal pelvis

22,999

185

0.80

2.31 (1.92, 2.78)

<0.001*

  Kidney

20,684

177

0.86

2.42 (2.01, 2.92)

<0.001*

  Renal pelvis

2,315

<11

<0.4

1.13 (0.56, 2.28)

0.7

 Thyroid

5,520

25

0.45

1.29 (0.85, 1.93)

0.2

 Non-Hodgkin lymphoma

50,513

120

0.24

0.77 (0.62, 0.96)

0.02

 Multiple myeloma

13,949

92

0.66

1.77 (1.40, 2.24)

<0.001*

 Acute myeloid leukemia

7,571

25

0.33

1.02 (0.67, 1.53)

0.9

 Chronic myeloid leukemia

3,271

18

0.55

1.74 (1.08, 2.80)

0.02

  1. Abbreviations: ESRD end-stage renal disease, OR odds ratio, CI confidence interval.
  2. Odds ratios are adjusted for age, race, sex and selection year. Cancers with less than 3000 cases are not shown.
  3. * P-value is significant at Bonferroni p-value threshold of 0.002.