Table 3 Crude and multivariate-adjusted odds ratios of upper quartile RBPCR

Age (per 10 years increase)

1.65 (1.24, 2.19)

<0.001

1.16 (0.82, 1.64)

0.46

Gender (male v female)

1.82 (0.99, 3.31)

0.05

Black ethnicity

0.36 (0.22, 0.61)

<0.0001

0.43 (0.24, 0.77)

0.005

Hypertension

1.37 (0.65, 2.89)

0.40

Diabetes

1.15 (0.29, 4.46)

0.84

HBsAg (positive)

0.44 (0.09, 2.00)

0.29

HCV Antibody (positive)

0.99 (0.04, 2.81)

0.98

eGFR

≥90 mL/min/1.73 m2

1

1

75-89 mL/min/1.73 m2

1.91 (1.02, 3.57)

0.04

1.70 (0.88, 3.28)

0.13

<75 mL/min/1.73 m2

5.52 (2.78, 10.9)

<0.0001

3.54 (1.61, 7.80)

0.001

Time since HIV diagnosis (per year increase)

1.08 (1.03, 1.14)

0.003

1.02 (0.96, 1.08)

0.4

Nadir CD4 count (per 50 cell increase)

1.03 (0.95, 1.12)

0.47

Current CD4 count (per 50 cell increase)

1.03 (0.98, 1.09)

0.28

Current HIV RNA <50 c/mL

0.86 (0.51, 1.47)

0.61

AIDS (CDC status C)

0.86 (0.04, 1.66)

0.65

cART status

not on cART

1

1

on cART not containing TFV

1.13 (0.53, 2.37)

0.76

1.23 (0.51, 2.99)

0.65

on TFV/NNRTI

1.16 (0.50, 2.68)

0.73

1.06 (0.40, 2.78)

0.91

on TFV/PI

2.50 (1.04, 5.98)

0.04

2.40 (0.84, 6.86)

0.10