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Table 3 Crude and multivariate-adjusted odds ratios of upper quartile RBPCR

From: Total protein, albumin and low-molecular-weight protein excretion in HIV-positive patients

  OR (95 % CI) P-value Adjusted OR (95 % CI) P-value
Age (per 10 years increase) 1.65 (1.24, 2.19) <0.001 1.16 (0.82, 1.64) 0.46
Gender (male v female) 1.82 (0.99, 3.31) 0.05   
Black ethnicity 0.36 (0.22, 0.61) <0.0001 0.43 (0.24, 0.77) 0.005
Hypertension 1.37 (0.65, 2.89) 0.40   
Diabetes 1.15 (0.29, 4.46) 0.84   
HBsAg (positive) 0.44 (0.09, 2.00) 0.29   
HCV Antibody (positive) 0.99 (0.04, 2.81) 0.98   
eGFR     
≥90 mL/min/1.73 m2 1   1  
75-89 mL/min/1.73 m2 1.91 (1.02, 3.57) 0.04 1.70 (0.88, 3.28) 0.13
<75 mL/min/1.73 m2 5.52 (2.78, 10.9) <0.0001 3.54 (1.61, 7.80) 0.001
Time since HIV diagnosis (per year increase) 1.08 (1.03, 1.14) 0.003 1.02 (0.96, 1.08) 0.4
Nadir CD4 count (per 50 cell increase) 1.03 (0.95, 1.12) 0.47   
Current CD4 count (per 50 cell increase) 1.03 (0.98, 1.09) 0.28   
Current HIV RNA <50 c/mL 0.86 (0.51, 1.47) 0.61   
AIDS (CDC status C) 0.86 (0.04, 1.66) 0.65   
cART status     
not on cART 1   1  
on cART not containing TFV 1.13 (0.53, 2.37) 0.76 1.23 (0.51, 2.99) 0.65
on TFV/NNRTI 1.16 (0.50, 2.68) 0.73 1.06 (0.40, 2.78) 0.91
on TFV/PI 2.50 (1.04, 5.98) 0.04 2.40 (0.84, 6.86) 0.10
  1. RBPCR = retinol-binding protein-creatinine ratio (urine);