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Table 3 Comparison of blood pressure, renal function, serum albumin, and urine sodium and potassium after treatment with furosemide alone or with the combination of furosemide plus albumin in chronic kidney disease patients

From: The added-up albumin enhances the diuretic effect of furosemide in patients with hypoalbuminemic chronic kidney disease: a randomized controlled study

 

Furosemide

Furosemide + Albumin

P-value

Mean ± SD

Mean ± SD

 

Blood pressure (mmHg)

   

6 hours systolic

132.0 ± 5.1

132.4 ± 6.2

0.60

diastolic

80.1 ± 5.3

80.6 ± 5.3

0.52

24 hours systolic

131.6 ±4.6

132.0 ±5.6

0.60

diastolic

79.7 ± 5.3

80.2 ± 5.5

0.57

Calculated GFR (mL/min/1.732)

   

6 hours

27.8 ± 12.6

27.2 ± 10.5

0.64

24 hours

29.1 ± 12.3

28.3 ± 11.3

0.23

Serum albumin (g/dL)

   

6 hours

2.98 ± 0.30

3.46 ± 0.42

< 0.01

24 hours

2.97 ± 0.31

3.42 ± 0.41

< 0.01

Urine volume at 6 hours (L)

0.90 ± 0.35

1.07 ± 0.34

0.02

Urine volume at 24 hours (L)

2.44 ± 0.74

2.47 ± 0.60

0.81

Urine sodium at 6 hours (mEq)

54.9 ± 31.6

70.8 ± 31.3

< 0.01

Urine sodium at 24 hours (mEq)

146.8 ± 59.9

154.4 ± 42.2

0.53

Urine potassium at 6 hours (mEq)

14.7 ± 8.0

18.0 ± 8.9

0.03

Urine potassium at 24 hours (mEq)

40.5 ± 10.0

40.3 ± 7.4

0.95

  1. GFR = Glomerular filtration rate SD = standard deviation.