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Table 2 Linear regression analysis for risk factors for decreased estimated glomerular filtration rate

From: Urinary N-acetyl-β-D glucosaminidase as a surrogate marker for renal function in autosomal dominant polycystic kidney disease: 1 year prospective cohort study

Parameters

Univariable

Multivariable

B (95 % CI)

Pvalue

B (95 % CI)

Pvalue

Age (yr)

−1.4 (−1.6 to −1.1)

< 0.001

−1.1 (−1.3 to −0.8)

< 0.001

Gender

0.7 (−4.7 to 6.2)

0.797

5.1 (0.7 to 9.5)

0.022

Years from diagnosis

−1.3 (−1.7 to −0.9)

< 0.001

-

-

Hypertension

−23.4 (−29.2 to −17.6)

< 0.001

−8.5 (−14.0 to −3.0)

0.003

Albumin/Cr (mg/g)

−9.3 (−11.7 to −7.0)

< 0.001

−5.6 (−7.6 to −3.6)

< 0.001

NAG/Cr (IU/g)

−16.5 (−20.7 to −12.3)

< 0.001

−4.5 (−8.6 to −0.5)

0.03

  1. Data were adjusted for age, years from diagnosis, hypertension and albuminuria. Albumin/Cr and NAG/Cr were log-transformed to fulfill the requirement of normal distribution of residuals. Cr, creatinine; NAG, N-Acetyl-β-D-glucosaminidase.