Urine concentrations of kidney injury molecule-1 (Kim-1) and neutrophil gelatinase-associated lipocalin (NGAL). A: The urine concentration of Kim-1 is markedly increased in CsA-only treated rats, and is significantly reduced by BIL administration. B: The urine concentration of NGAL is markedly increased in CsA-only treated rats, and urine NGAL shows a decreasing tendency in BIL-treated rats. The data are the means ± SD. *P < 0.05 vs. VH, †P < 0.05 vs. BIL, and ‡P < 0.05 vs. CsA.