Bilirubin (BIL) ameliorates apoptosis in CsA-induced nephropathy (CIN). Representative TUNEL staining of the renal cortex in CIN. A: Vehicle (VH), B: Bilirubin (BIL) C: CsA, and D: BIL + CsA groups (magnification × 400). E: The percentage of apoptotic cells (TUNEL-positive cells) was obtained in at least 10 fields from the A , B and C groups. The data are the means ± SD. *P < 0.05 vs. VH, †P < 0.05 vs. BIL, and ‡P < 0.05 vs. CsA.