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Table 1 Characteristics among patients discharged on clopidogrel at hospital discharge by eGFR strata

From: Chronic kidney disease is associated with adverse outcomes among elderly patients taking clopidogrel after hospitalization for acute coronary syndrome

  Overall (n = 7413) eGFR > = 60 ml/min/m2 (n = 3997) eGFR 30–60 ml/min/m2 (n = 2559) eGFR < 30 ml/min/m2 (n = 857) p-value
Age (mean +/− SD) 66.3 (11.2) 61.9 (9.9) 71.2 (10.5) 71.9 (10.5) <0.001
Male sex (%, n) 98 (7294) 98 (3936) 98 (2513) 99 (845) 0.61
White race (%, n) 80 (5963) 82 (3269) 81 (2083) 71 (611) <0.001
Medical conditions (%, n)
  Diabetes 42 (3139) 35 (1385) 47 (1209) 64 (545) <0.001
  Hypertension 28 (2101) 21 (843) 33 (840) 49 (418) <0.001
  H/o MI 19 (1410) 17 (692) 21 (544) 20 (174) <0.001
  CHF 13 (999) 6 (227) 18 (453) 37 (319) <0.001
  Stroke 2 (172) 2 (65) 3 (75) 4 (32) <0.001
  PAD 13 (974) 10 (398) 15 (395) 21 (181) <0.001
  Lipid disorder 76 (5627) 77 (3070) 77 (1976) 68 (581) <0.001
  Liver disease 2 (177) 3 (108) 2 (50) 2 (19) 0.15
  COPD 12 (902) 11 (439) 14 (355) 13 (108) .002
  Cancer 5 (388) 5 (182) 6 (155) 6 (51) .017
  Dementia 4 (309) 4 (152) 5 (119) 4 (38) 0.226
  Depression 9 (642) 10 (399) 8 (196) 5 (47) <0.001
Current smoker (%, n) 31 (2333) 42 (1681) 21 (537) 13 (115) <0.001
LVEF (%, n)      <0.001
  EF > = 40% 73 (5430) 78 (3121) 70 (1786) 61 (523)  
  EF < 40% 22 (1622) 16 (630) 27 (688) 35 (304)  
  missing 5 (361) 6 (246) 3 (85) 4 (30)  
Procedure (%, n)      <0.001
  No PCI 41 (2990) 31 (1215) 47 (1208) 66 (567)  
  PCI/no stent 2 (175) 3 (109) 2 (47) 2 (19)  
  PCI/BMS 13 (929) 14 (540) 12 (311) 9 (78)  
  PCI/DES 45 (3287) 53 (2111) 39 (984) 22 (192)  
TIMI > = 3 (%, n) 59 (4371) 48 (1901) 71 (1821) 76 (649) <0.001
Glycoprotein inhibitor (%, n) 46 (3394) 53 (2130) 41 (1059) 24 (205)  
Hospital discharge medications (%, n)
  ASA 95 (7016) 96 (3821) 94 (2404) 92 (791) <0.001
  Beta-blocker 93 (6925) 94 (3752) 93 (2375) 93 (798) 0.223
  ACE-I 71 (5276) 77 (3068) 70 (1799) 48 (409) <0.001
  ARB 9 (644) 6 (256) 11 (280) 13 (108) <0.001
  heparin 4 (264) 4 (142) 4 (100) 3 (22) 0.186