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Table 1 Clinical characteristics and biochemical data of patients with impaired kidney function stratified into two groups based on cardiac function

From: B-type natriuretic peptide versus amino terminal pro-B type natriuretic peptide: selecting the optimal heart failure marker in patients with impaired kidney function

Characteristics of total subjects p value
  Mean (±SD), n (%)  
  Overall Without SHF With SHF  
  n = 190 n = 95 n = 95  
Age (years) 58 ± 15 53 ± 15 63 ± 14 0.00
Male gender (%) 128 (67.4) 59 (62.1) 69 (72.6) 0.12
BMI (kg/m 2 ) 23 ± 3.1 24.1 ± 3.2 21.9 ± 2.5 0.00
Hypertension (%) 141 (74.6) 71 (74.7) 70 (73.7) 0.77
Anemia (%) 129 (67.9) 64 (67.4) 65 (68.4) 0.87
Diabetes (%) 108 (56.8) 49 (51.6) 59 (62.1) 0.14
Dyslipidemia (%) 69 (36.3) 33 (34.7) 36 (37.9) 0.65
Ischemic heart disease (%) 39 (20.5) 0 39 (41.1) 0.00
Smoking history (%) 6 (3.2) 1 (1.1) 5 (5.3) 0.09
Cerebrovascular accident (%) 4 (2.1) 1 (1.1) 3 (3.2) 0.31
Malignancy (%) 1 (0.5) 0 1 (1.1) 0.31
Alcohol intake (%) 1 (0.5) 1 (1.1) 0 0.31
ACE inhibitors 91 (47.9) 51 (53.7) 40 (42.1) 0.11
Statins 69 (36.3) 33 (34.7) 36 (37.9) 0.65
Calcium channel blockers 49 (25.8) 32 (33.7) 17 (17.9) 0.01
Diuretics 41 (21.6) 19 (20) 22 (23.2) 0.59
Digoxin 22 (11.6) 0 22 (23.2) 0.00
ARB 20 (10.5) 8 (8.4) 12 (12.6) 0.34
Beta blocker 13 (6.8) 12 (12.6) 1 (1.1) 0.00
Stage 3 CKD (%) 77 (40.5) 41 (43.2) 36 (37.9) 0.75
Stage 4 CKD (%) 77 (40.5) 37 (38.9) 40 (42.1) 0.75
Stage 5 CKD (%) 36 (18.9) 17 (17.9) 19 (20) 0.49
Ejection fraction (%) 42.9 ± 6.8 59.3 ± 3.5 26.6 ±10.2 0.00
eGFR (ml/min) 27.7 ± 14 29.1 ± 15.1 26.2 ± 12.9 0.15
Cr (mg/dl) 3.2 ± 2.2 3.3 ± 2.4 3.0 ± 1.8 0.34
Log BNP (pg/ml) 2.2 ± 0.5 2.0 ± 0.4 2.4 ± 0.6 0.00
Log NT-proBNP (pg/ml) 3.4 ± 0.6 2.9 ± 0.6 3.9 ± 0.6* 0.00
  1. Abbreviations: SHF systolic heart failure, SD standard deviation, BMI body mass index, ACE angiotensin converting enzyme, ARB angiotensin receptor blocker, CKD chronic kidney disease, eGFR estimated glomerular filtration rate, Cr creatinine, BNP b type natriuretic peptide, NT-proBNP Amino terminal B-type natriuretic peptide.