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Table 4 Potential BNP and NT-proBNP cut off levels for the assessment of systolic heart failure according CKD staging

From: B-type natriuretic peptide versus amino terminal pro-B type natriuretic peptide: selecting the optimal heart failure marker in patients with impaired kidney function

Natriuretic peptide Group Optimal cut point (pg/ml) Sensitivity Specificity
    % %
BNP Stage 3 CKD 146 60 65.9
BNP Stage 4 CKD 309.4 60 78.4
BNP Stage 5 CKD 491 60 88.2
NT-proBNP Stage 3 CKD 1505.8 72.2 92.7
NT-proBNP Stage 4 CKD 7767.5 70 91.9
NT-proBNP Stage 5 CKD 11215.2 94.7 100
  1. Abbreviations: BNP B-type natriuretic peptide, NT-proBNP amino terminal B-type natriuretic peptide, AUC area under the curve, CKD chronic kidney disease.