Table 4 Incidence of acute kidney injury in critically ill pH1N1 patients using different definitions of baseline renal function
Primary analysis, with baseline glomerular filtration rate estimated as 75 ml/min/1.73 m2 | Incidence | Hospital mortality1, 2 |
|---|---|---|
(n = 562) | ||
No AKI | 220 (39.1) | 28/216 (13.0) |
None | 181 (32.2) | 21/178 (11.8) |
Risk | 39 (6.9) | 7/38 (18.4) |
AKI | 342 (60.9) | 85/329 (25.8) |
Injury | 129 (23.0) | 20/125 (16.0) |
Failure | 213 (37.9) | 65/204 (31.9) |
Renal replacement therapy, n = 561 | 85 (15.1) | 26/84 (31.0) |
Injury | 3 (0.5%) | 3/3 (100) |
Failure | 82 (14.6%) | 26/81 (31.0%) |
Sensitivity analysis 1, assuming that first available serum creatinine is the baseline | n = 537 | |
No AKI | 269 (50.1) | 45/262 (17.2) |
None | 221 (41.2) | 26/217 (12.0) |
Risk | 48 (8.9) | 19/45 (42.2) |
AKI | 268 (49.9) | 64/259 (24.7) |
Injury | 253 (47.1) | 61/244 (25.0) |
Failure | 15 (2.8) | 3/15 (20.0) |
Sensitivity analysis 2, assuming that lowest observed serum creatinine at any time is the baseline | n = 562 | |
No AKI | 218 (38.8) | 27/214 (12.6) |
None | 194 (34.5%) | 25/191 (13.1) |
Risk | 24 (4.2%) | 2/23 (8.7) |
AKI | 344 (61.2) | 86/331 (26.0) |
Injury | 118 (21.0%) | 15/114 (13.2) |
Failure3 | 226 (40.2%) | 71/217 (32.7) |