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Table 1 Patient characteristics at the time of diagnosis

From: Validation of a newly proposed histopathological classification in Japanese patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

  Total (n = 102) Non-ESRD (n = 79) ESRD during follow-up (n = 23) pvalue
Age (years) 66.3 ± 11.3 66.3 ± 12.2 66.3 ± 7.7 n.s.
Male/female, n 54/48 39/40 15/8 n.s.
MPO-ANCA, n 86 70 16  
PR3-ANCA, n 5 4 1  
Both negative, n 11 5 6  
eGFR (ml/min/1.73 m2) 21.6 (11.5–39.5) 25.7 (17.4–50.4) 9.0 (5.1–13.3) <0.001
Serum albumin (g/dl) 3.1 (2.7–3.7) 3.1 (2.7–3.7) 3.1 (2.7–3.8) n.s.
Serum CRP (mg/dl) 3.35 (0.98–8.98) 3.70 (1.08–10.0) 2.13 (0.20–6.70) n.s.
Proteinuria (g/day) 1.10 (0.35–2.12) 0.70 (0.30–1.77) 1.80 (1.10–2.50) <0.01
  1. Data are expressed as mean ± SD or median (interquartile range). p values were calculated using the Mann–Whitney U test or Fisher’s exact test. Statistical significance was defined as p < 0.05.
  2. Abbreviations: ESRD end-stage renal disease, ns not significant, eGFR estimated glomerular filtration rate, MPO myeloperoxidase, PR3 proteinase-3, CRP C-reactive protein.