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Table 1 Patient characteristics at the time of diagnosis

From: Validation of a newly proposed histopathological classification in Japanese patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

 

Total (n = 102)

Non-ESRD (n = 79)

ESRD during follow-up (n = 23)

pvalue

Age (years)

66.3 ± 11.3

66.3 ± 12.2

66.3 ± 7.7

n.s.

Male/female, n

54/48

39/40

15/8

n.s.

MPO-ANCA, n

86

70

16

 

PR3-ANCA, n

5

4

1

 

Both negative, n

11

5

6

 

eGFR (ml/min/1.73 m2)

21.6 (11.5–39.5)

25.7 (17.4–50.4)

9.0 (5.1–13.3)

<0.001

Serum albumin (g/dl)

3.1 (2.7–3.7)

3.1 (2.7–3.7)

3.1 (2.7–3.8)

n.s.

Serum CRP (mg/dl)

3.35 (0.98–8.98)

3.70 (1.08–10.0)

2.13 (0.20–6.70)

n.s.

Proteinuria (g/day)

1.10 (0.35–2.12)

0.70 (0.30–1.77)

1.80 (1.10–2.50)

<0.01

  1. Data are expressed as mean ± SD or median (interquartile range). p values were calculated using the Mann–Whitney U test or Fisher’s exact test. Statistical significance was defined as p < 0.05.
  2. Abbreviations: ESRD end-stage renal disease, ns not significant, eGFR estimated glomerular filtration rate, MPO myeloperoxidase, PR3 proteinase-3, CRP C-reactive protein.
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BMC Nephrology

ISSN: 1471-2369

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