Table 2 Baseline characteristics of patients in each histopathological class

Age (years)

66.1 ± 11.4

66.3 ± 12.5

66.7 ± 10.2

67.5 ± 8.6

n.s.

Male/female, n

24/22

15/17

10/8

5/1

n.s.

MPO-ANCA, n

40

26

15

5

n.s.

PR3-ANCA, n

3

2

0

0

Both negative, n

3

4

3

1

eGFR (ml/min/1.73 m²)

38.1 (22.5–57.4)

12.0 (7.1–19.7)

16.5 (8.7–31.6)

12.4 (9.8–27.4)

<0.0001

Serum albumin (g/dl)

3.4 (2.8–3.7)

2.7 (2.4–3.3)

3.1 (2.8–3.7)

3.8 (3.5–3.9)

<0.01

Serum CRP (mg/dl)

4.13 (1.43–9.62)

4.98 (1.65–14.0)

1.21 (0.10–3.93)

0.16 (0.10–1.10)

<0.001

Proteinuria (g/day)

0.35 (0.21–0.79)

1.50 (1.04–2.50)

1.75 (1.07–2.20)

1.50 (0.25–3.98)

<0.0001

Immunosuppressants, yes/no, n

25/21

17/15

4/14

1/5

<0.05

Histopathological findings

Normal glomeruli (%)

73.2 (60.0–81.6)

17.9 (10.6–28.0)

35.4 (22.5–43.8)

11.3 (0–22.0)

<0.0001

Crescentic glomeruli (%)

13.8 (8.9–23.6)

67.7 (60.0–74.7)

31.4 (15.6–40.4)

12.4 (3.3–22.4)

<0.0001

Globally sclerotic glomeruli (%)

6.5 (0–13.4)

3.2 (0–13.1)

29.3 (19.0–40.4)

64.5 (54.9–71.1)

<0.0001