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Table 3 Minor allele frequencies, genotype counts and logistic regression model adjusted for collection centre, gender, duration of type 1 diabetes, and average HbA1c

From: Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy

Chra Position Gene SNP ID Allele Case count MAF Control count MAF ORb C.I.c Pd
2 219428221 WNT6 rs940469 [T/C] 24/170/483 0.16 24/170/483 0.18 0.86 0.67 - 1.11 0.25
2 219430908 WNT6 rs690877 [T/C] 56/276/360 0.28 56/276/360 0.27 0.92 0.74 - 1.14 0.43
2 219440386 WNT6 rs6754599 [G/C] 18/166/494 0.15 18/166/494 0.17 0.85 0.65 - 1.11 0.22
2 219458990 WNT6 rs2385199 [G/A] 23/200/471 0.18 23/200/471 0.19 0.90 0.7 - 1.16 0.43
3 41205327 CTNNB1 rs2691678 [C/T] 51/250/390 0.25 51/250/390 0.25 1.01 0.81 - 1.26 0.91
3 41243358 CTNNB1 rs11564447 [G/T] 1/59/634 0.04 1/59/634 0.04 0.91 0.57 - 1.43 0.68
3 41254444 CTNNB1 rs4135385 [G/A] 49/237/398 0.24 49/237/398 0.23 1.04 0.84 - 1.3 0.70
3 55450313 WNT5A rs815533 [A/G] 22/206/466 0.18 22/206/466 0.17 1.27 0.99 - 1.64 0.06
3 55456115 WNT5A rs3913369 [T/G] 33/261/394 0.24 33/261/394 0.23 0.91 0.72 - 1.14 0.40
3 55466053 WNT5A rs629537 [A/G] 11/145/534 0.12 11/145/534 0.13 0.89 0.67 - 1.18 0.40
3 55467090 WNT5A rs845542 [C/T] 44/272/377 0.26 44/272/377 0.25 1.19 0.95 - 1.49 0.13
3 55494897 WNT5A rs648872 [T/C] 13/172/501 0.14 13/172/501 0.17 0.86 0.67 - 1.1 0.22
3 55495818 WNT5A rs566926 [T/G] 49/252/368 0.26 49/252/368 0.27 0.99 0.8 - 1.24 0.96
3 121016036 GSK3B rs11917714 [T/C] 19/205/470 0.18 19/205/470 0.16 1.02 0.79 - 1.31 0.89
3 121018485 GSK3B rs11929668 [G/C] 22/170/501 0.15 22/170/501 0.18 0.87 0.67 - 1.12 0.27
3 121133839 GSK3B rs17204365 [C/T] 2/41/648 0.03 2/41/648 0.03 1.61 0.91 - 2.85 0.10
3 121157741 GSK3B rs17810235 [T/C] 74/303/312 0.33 74/303/312 0.29 1.33 1.09 - 1.64 0.01
3 121300363 GSK3B rs17471 [A/T] 3/110/581 0.08 3/110/581 0.09 0.67 0.47 - 0.95 0.02
3 121306727 GSK3B rs11927974 [A/G] 8/101/584 0.08 8/101/584 0.09 0.98 0.71 - 1.35 0.89
3 121307901 GSK3B rs334538 [A/G] 22/191/481 0.17 22/191/481 0.19 0.89 0.7 - 1.14 0.35
3 121308854 GSK3B rs12053912 [T/A] 17/186/485 0.16 17/186/485 0.14 1.21 0.92 - 1.58 0.18
3 121315311 GSK3B rs334543 [C/A] 66/311/307 0.32 66/311/307 0.35 0.79 0.65 - 0.97 0.02
4 108055760 DKK2 rs429941 [G/A] 53/282/356 0.28 53/282/356 0.28 1.08 0.88 - 1.34 0.46
4 108062942 DKK2 rs10488898 [A/G] 2/77/603 0.06 2/77/603 0.07 0.85 0.58 - 1.24 0.40
4 108065243 DKK2 rs17037102 [A/G] 7/132/526 0.11 7/132/526 0.10 1.17 0.85 - 1.6 0.34
4 108084260 DKK2 rs10488899 [G/T] 42/237/410 0.23 42/237/410 0.21 1.10 0.88 - 1.39 0.40
4 108110470 DKK2 rs17509845 [A/G] 1/66/622 0.05 1/66/622 0.05 1.08 0.69 - 1.7 0.74
4 108120464 DKK2 rs17618172 [G/A] 20/219/445 0.19 20/219/445 0.20 1.01 0.79 - 1.28 0.96
4 108135958 DKK2 rs7690634 [A/T] 9/165/515 0.13 9/165/515 0.12 1.19 0.89 - 1.58 0.24
4 108165736 DKK2 rs4956277 [C/A] 30/246/396 0.23 30/246/396 0.24 0.94 0.75 - 1.17 0.58
4 108170809 DKK2 rs10021344 [G/A] 150/357/185 0.47 150/357/185 0.48 0.99 0.82 - 1.19 0.88
4 108173328 DKK2 rs956137 [A/C] 4/111/577 0.09 4/111/577 0.08 1.28 0.92 - 1.8 0.15
4 108173463 DKK2 rs6827902 [C/A] 28/237/416 0.22 28/237/416 0.21 1.15 0.91 - 1.45 0.23
4 108181414 DKK2 rs6823507 [C/T] 1/88/593 0.07 1/88/593 0.08 0.87 0.6 - 1.26 0.46
4 108185493 DKK2 rs419178 [C/T] 38/272/379 0.25 38/272/379 0.27 0.86 0.69 - 1.07 0.17
4 108199999 DKK2 rs398093 [T/C] 12/138/510 0.12 12/138/510 0.12 1.09 0.81 - 1.46 0.58
4 108200154 DKK2 rs17510191 [C/T] 20/251/423 0.21 20/251/423 0.18 1.13 0.89 - 1.43 0.31
7 120727672 WNT16 rs2707521 [T/C] 103/338/239 0.40 103/338/239 0.41 0.90 0.74 - 1.1 0.32
7 120738146 WNT16 rs13247600 [C/G] 3/81/610 0.06 3/81/610 0.07 1.08 0.74 - 1.57 0.69
7 120738380 WNT16 rs2707520 [G/T] 166/340/183 0.49 166/340/183 0.49 1.12 0.92 - 1.35 0.25
7 120741508 WNT16 rs983926 [A/G] 6/101/587 0.08 6/101/587 0.09 0.93 0.67 - 1.3 0.68
7 120751201 WNT16 rs3757552 [C/T] 9/151/534 0.12 9/151/534 0.12 0.89 0.67 - 1.19 0.44
7 120762001 WNT16 rs3801387 [C/T] 69/283/340 0.30 69/283/340 0.29 1.00 0.81 - 1.23 0.99
7 120774586 WNT16 rs2707461 [T/C] 18/187/489 0.16 18/187/489 0.17 0.98 0.77 - 1.26 0.89
14 58696138 DAAM1 rs8016068 [T/C] 4/176/514 0.13 4/176/514 0.12 1.09 0.81 - 1.47 0.57
14 58713714 DAAM1 rs17095819 [G/A] 15/185/477 0.16 15/185/477 0.13 1.28 0.96 - 1.71 0.09
14 58728544 DAAM1 rs1252906 [G/T] 19/164/511 0.15 19/164/511 0.18 0.75 0.58 - 0.97 0.03
14 58826755 DAAM1 rs7155987 [T/C] 18/180/496 0.16 18/180/496 0.14 1.10 0.84 - 1.44 0.48
14 58833620 DAAM1 rs12878138 [T/C] 2/99/593 0.07 2/99/593 0.07 0.96 0.67 - 1.39 0.84
14 58861382 DAAM1 rs941882 [C/A] 40/238/416 0.23 40/238/416 0.23 1.03 0.82 - 1.28 0.82
14 58885779 DAAM1 rs17834014 [G/A] 3/86/605 0.07 3/86/605 0.08 0.97 0.67 - 1.42 0.88
14 58886484 DAAM1 rs12880248 [A/G] 12/177/505 0.14 12/177/505 0.14 1.06 0.8 - 1.39 0.70
14 58889427 DAAM1 rs12878070 [G/T] 150/334/210 0.46 150/334/210 0.42 1.10 0.91 - 1.32 0.33
14 58908520 DAAM1 rs17096179 [C/A] 5/104/585 0.08 5/104/585 0.09 0.88 0.63 - 1.24 0.47
14 58913159 DAAM1 rs1253192 [A/G] 5/80/609 0.06 5/80/609 0.09 0.65 0.46 - 0.93 0.02
16 275374 AXIN1 rs2685127 [T/C] 7/157/529 0.12 7/157/529 0.13 1.02 0.76 - 1.36 0.92
16 276397 AXIN1 rs400037 [T/C] 32/243/410 0.22 32/243/410 0.22 0.97 0.77 - 1.21 0.77
16 281080 AXIN1 rs12925669 [A/G] 22/171/501 0.15 22/171/501 0.16 1.06 0.82 - 1.37 0.65
16 289294 AXIN1 rs214246 [C/T] 148/349/196 0.47 148/349/196 0.49 0.93 0.77 - 1.12 0.45
16 303385 AXIN1 rs12930863 [C/T] 20/175/490 0.16 20/175/490 0.16 1.05 0.81 - 1.36 0.70
16 313818 AXIN1 rs11646942 [A/C] 51/261/355 0.27 51/261/355 0.31 0.89 0.72 - 1.1 0.29
16 333343 AXIN1 rs395901 [A/G] 7/115/569 0.09 7/115/569 0.09 0.82 0.6 - 1.14 0.24
16 336265 AXIN1 rs1805105 [A/G] 67/310/284 0.34 67/310/284 0.31 1.19 0.97 - 1.47 0.10
16 68112382 NFAT5 rs12921716 [A/G] 6/113/575 0.09 6/113/575 0.08 0.95 0.68 - 1.32 0.75
16 68117197 NFAT5 rs4783720 [C/T] 22/184/488 0.16 22/184/488 0.15 1.10 0.85 - 1.43 0.47
16 68200854 NFAT5 rs17297207 [G/A] 3/69/612 0.05 3/69/612 0.07 0.66 0.44 - 0.98 0.04
16 68203623 NFAT5 rs11639947 [T/C] 22/183/467 0.17 22/183/467 0.21 0.80 0.63 - 1.02 0.07
16 68281721 NFAT5 rs1064825 [A/G] 0/74/619 0.05 0/74/619 0.06 0.84 0.55 - 1.28 0.42
16 68290961 NFAT5 rs7359336 [G/A] 128/329/227 0.43 128/329/227 0.41 1.04 0.86 - 1.26 0.69
17 42163544 WNT3 rs35937770 [A/G] 83/321/283 0.35 83/321/283 0.35 0.99 0.81 - 1.21 0.90
17 42188384 WNT3 rs35732828 [A/C] 19/200/466 0.17 19/200/466 0.17 1.05 0.81 - 1.35 0.71
17 42209035 WNT3 rs199520 [G/A] 38/237/419 0.23 38/237/419 0.22 1.04 0.83 - 1.3 0.75
17 42221887 WNT3 rs199496 [A/G] 5/117/569 0.09 5/117/569 0.07 1.11 0.78 - 1.58 0.56
17 42221965 WNT3 rs11658976 [G/A] 129/338/227 0.43 129/338/227 0.42 1.03 0.85 - 1.25 0.74
17 42223260 WNT3 rs11655598 [G/C] 46/249/387 0.25 46/249/387 0.29 0.94 0.76 - 1.16 0.57
17 42223353 WNT3 rs12452064 [A/G] 147/322/211 0.45 147/322/211 0.43 1.08 0.9 - 1.3 0.42
17 42224733 WNT3 rs10432043 [T/C] 86/301/284 0.35 86/301/284 0.33 1.07 0.88 - 1.31 0.50
17 42234514 WNT3 rs7207916 [A/G] 113/313/267 0.39 113/313/267 0.43 0.93 0.77 - 1.12 0.43
17 42243374 WNT3 rs11079737 [A/G] 54/268/338 0.28 54/268/338 0.27 1.12 0.91 - 1.38 0.30
17 42259048 WNT3 rs11079738 [G/A] 143/362/188 0.47 143/362/188 0.47 1.02 0.84 - 1.23 0.88
17 42261948 WNT3 rs8069437 [T/C] 35/225/433 0.21 35/225/433 0.23 0.85 0.68 - 1.07 0.16
19 51775092 CALM3 rs8103534 [C/T] 63/298/333 0.31 63/298/333 0.31 0.96 0.78 - 1.18 0.67
19 51781925 CALM3 rs4274528 [T/C] 7/144/542 0.11 7/144/542 0.12 1.17 0.87 - 1.57 0.31
19 51790267 CALM3 rs7260181 [C/T] 146/355/193 0.47 146/355/193 0.46 1.08 0.89 - 1.31 0.43
19 51798474 CALM3 rs4380146 [G/T] 69/284/327 0.31 69/284/327 0.32 1.03 0.84 - 1.26 0.76
19 51800325 CALM3 rs11671131 [C/T] 12/167/513 0.14 12/167/513 0.14 0.87 0.67 - 1.14 0.32
19 51804580 CALM3 rs710889 [A/G] 94/315/285 0.36 94/315/285 0.36 0.93 0.76 - 1.13 0.47
19 51804978 CALM3 rs10405893 [A/G] 5/153/535 0.12 5/153/535 0.11 1.25 0.92 - 1.69 0.16
19 51811750 CALM3 rs11083840 [G/T] 118/341/235 0.42 118/341/235 0.44 0.91 0.75 - 1.1 0.32
19 51811873 CALM3 rs11083841 [G/A] 26/181/457 0.18 26/181/457 0.16 1.15 0.9 - 1.47 0.26
  1. aChr = Chromosome.
  2. bOR = Odds Ratio.
  3. cC.I. = 95% Confidence Interval.
  4. dP-value, not corrected for multiple testing.