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Table 4 Most significant results from logistic regression analyses

From: Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy

a. Single SNP analysis for diabetic nephropathy
Gene SNP a OR b C.I. c P
GSK3B rs17810235 1.23 1.03 - 1.45 0.022
NFAT5 rs11639947 0.79 0.64 - 0.97 0.023
AXIN1 rs11646942 0.82 0.68 - 0.97 0.026
DAAM1 rs17095819 1.27 1.01 - 1.59 0.045
DKK2 rs17510191 1.23 1.01 - 1.49 0.047
b. Adjusted logistic regression analysis for diabetic nephropathy
GSK3B rs17810235 1.33 1.09 - 1.64 0.006
DAAM1 rs1253192 0.65 0.46 - 0.93 0.018
GSK3B rs17471 0.67 0.47 - 0.95 0.025
GSK3B rs334543 0.79 0.65 - 0.97 0.025
DAAM1 rs1252906 0.75 0.58 - 0.97 0.027
NFAT5 rs17297207 0.66 0.44 - 0.98 0.040
c. Adjusted logistic regression analysis for end-stage renal disease
WNT3 rs11079737 1.50 1.13 - 1.98 0.005
DAAM1 rs1253192 0.43 0.23 - 0.81 0.009
DAAM1 rs941882 1.45 1.08 - 1.94 0.013
CALM3 rs8103534 0.68 0.50 - 0.92 0.013
DKK2 rs6827902 1.47 1.08 - 1.99 0.015
DAAM1 rs1252906 0.60 0.40 - 0.91 0.015
WNT3 rs11079738 1.33 1.02 - 1.74 0.035
DAAM1 rs7155987 1.43 1.02 - 2.02 0.040
DAAM1 rs17834014 1.61 1.01 - 2.55 0.045
WNT6 rs940469 0.68 0.47 - 0.99 0.046
  1. aOR: Odds Ratio.
  2. bC.I.: 95% Confidence Intervals.
  3. cP: value adjusted for collection centre, gender, duration of type 1 diabetes, and average HbA1c as covariates; not corrected for multiple testing.