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Table 2 Baseline characteristics and laboratory findings of the patients at the time of admission to the intensive care unit

From: Duration of acute kidney injury and mortality in critically ill patients: a retrospective observational study

 

No AKI (n = 488)

1sttertile (n = 552)

2ndtertile (n = 497)

3rdtertile (n = 437)

RRT (n = 169)

Age (years)

65.0 ± 16.11

66.8 ± 16.49

69.5 ± 15.40

69.7 ± 15.34

66.2 ± 14.30

Male sex (%)

52.5

63.9

59.6

59.3

68.0

Body weight (kg)

58.1 ± 11.61

59.0 ± 13.19

57.1 ± 11.94

57.8 ± 13.45

62.0 ± 11.09

Primary diagnosis

     

Cardiovascular disease

39.1

27.4

30.4

27.7

20.1

Sepsis

1.6

3.3

4.8

5.0

14.8

Surgical emergency

3.7

2.5

1.2

1.6

0.6

Others

55.5

66.7

63.6

65.7

64.5

Underlying CKD

5.5

6.9

9.3

9.8

22.5

History of malignancy

16.2

14.7

17.1

19.9

24.3

Need for MV

51.2

62.9

76.7

81.2

78.1

Use of vasoactive drugs

24.2

44.9

59.8

65.7

75.1

SBP (mmHg)

133.1 ± 31.37

132.3 ± 33.58

128.1 ± 35.15

128.4 ± 36.02

118.4 ± 32.54

DBP (mmHg)

71.1 ± 23.61

70.1 ± 26.18

64.8 ± 26.81

63.6 ± 28.42

56.2 ± 25.59

White blood cells (1000/mm3)*

9.5 (7.09–12.69)

10.7 (7.40–14.42)

10.9 (7.53 – 15.37)

10.4 (7.45–14.57)

10.1 (7.00–15.67)

Hemoglobin (g/dL)

12.8 ± 2.32

12.7 ± 2.63

12.0 ± 2.58

11.7 ± 2.74

10.8 ± 2.90

Platelet (1000/μL)*

237 (185–294)

217 (163–289)

214 (156–294)

217 (144–292)

177 (88–261)

Blood urea nitrogen (mg/dL)*

15 (11–20)

18 (13–26)

22 (14–34)

22 (14–39)

34 (20–66)

Creatinine (mg/dL)*

0.9 (0.7–1.1)

1.1 (0.8–1.3)

1.2 (0.9–1.7)

1.2 (0.8–1.9)

2.0 (1.1–3.9)

Cholesterol (mg/dL)

170.0 ± 49.48

161.5 ± 56.57

152.4 ± 52.38

153.2 ± 59.00

138.6 ± 50.88

Protein (g/dL)

6.6 ± 0.99

6.5 ± 1.03

6.4 ± 1.04

6.2 ± 1.05

6.1 ± 1.07

Bilirubin (mg/dL)*

0.7 (0.5–1.0)

0.8 (0.6–1.1)

0.8 (0.6–1.2)

0.7 (0.5–1.1)

0.9 (0.5–1.5)

GOT (mg/dL)*

26 (19–39)

31 (20–51)

33 (22–67)

31 (21–58)

36 (22–98)

GPT (mg/dL)*

22 (14–33)

22 (12–41)

22 (14–43)

23 (14–48)

28 (15–65)

Alkaline phosphatase (mg/dL)*

76 (63–99)

83 (63–106)

82 (64–112)

85 (65–118)

84 (66–122)

APACHE ІІ score

13.4 ± 6.51

16.7 ± 7.33

20.7 ± 7.80

20.3 ± 7.86

22.1 ± 8.51

LOS in hospital (days)*

16 (9–35)

21 (11–38)

22 (11–51)

29 (14–54)

13 (7–28)

  1. *Data are expressed as the median (interquartile range).
  2. Duration of acute kidney injury: 1st tertile, 1–2 days; 2nd tertile, 3–5 days; 3rd tertile, ≥ 6 days.
  3. AKI Acute kidney injury, RRT Renal replacement therapy, CKD Chronic kidney disease, MV Mechanical ventilation, SBP Systolic blood pressure, DBP Diastolic blood pressure, APACHE Acute Physiology and Chronic Health Evaluation, LOS Length of stay.