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Table 2 Baseline characteristics and laboratory findings of the patients at the time of admission to the intensive care unit

From: Duration of acute kidney injury and mortality in critically ill patients: a retrospective observational study

  No AKI (n = 488) 1sttertile (n = 552) 2ndtertile (n = 497) 3rdtertile (n = 437) RRT (n = 169)
Age (years) 65.0 ± 16.11 66.8 ± 16.49 69.5 ± 15.40 69.7 ± 15.34 66.2 ± 14.30
Male sex (%) 52.5 63.9 59.6 59.3 68.0
Body weight (kg) 58.1 ± 11.61 59.0 ± 13.19 57.1 ± 11.94 57.8 ± 13.45 62.0 ± 11.09
Primary diagnosis      
Cardiovascular disease 39.1 27.4 30.4 27.7 20.1
Sepsis 1.6 3.3 4.8 5.0 14.8
Surgical emergency 3.7 2.5 1.2 1.6 0.6
Others 55.5 66.7 63.6 65.7 64.5
Underlying CKD 5.5 6.9 9.3 9.8 22.5
History of malignancy 16.2 14.7 17.1 19.9 24.3
Need for MV 51.2 62.9 76.7 81.2 78.1
Use of vasoactive drugs 24.2 44.9 59.8 65.7 75.1
SBP (mmHg) 133.1 ± 31.37 132.3 ± 33.58 128.1 ± 35.15 128.4 ± 36.02 118.4 ± 32.54
DBP (mmHg) 71.1 ± 23.61 70.1 ± 26.18 64.8 ± 26.81 63.6 ± 28.42 56.2 ± 25.59
White blood cells (1000/mm3)* 9.5 (7.09–12.69) 10.7 (7.40–14.42) 10.9 (7.53 – 15.37) 10.4 (7.45–14.57) 10.1 (7.00–15.67)
Hemoglobin (g/dL) 12.8 ± 2.32 12.7 ± 2.63 12.0 ± 2.58 11.7 ± 2.74 10.8 ± 2.90
Platelet (1000/μL)* 237 (185–294) 217 (163–289) 214 (156–294) 217 (144–292) 177 (88–261)
Blood urea nitrogen (mg/dL)* 15 (11–20) 18 (13–26) 22 (14–34) 22 (14–39) 34 (20–66)
Creatinine (mg/dL)* 0.9 (0.7–1.1) 1.1 (0.8–1.3) 1.2 (0.9–1.7) 1.2 (0.8–1.9) 2.0 (1.1–3.9)
Cholesterol (mg/dL) 170.0 ± 49.48 161.5 ± 56.57 152.4 ± 52.38 153.2 ± 59.00 138.6 ± 50.88
Protein (g/dL) 6.6 ± 0.99 6.5 ± 1.03 6.4 ± 1.04 6.2 ± 1.05 6.1 ± 1.07
Bilirubin (mg/dL)* 0.7 (0.5–1.0) 0.8 (0.6–1.1) 0.8 (0.6–1.2) 0.7 (0.5–1.1) 0.9 (0.5–1.5)
GOT (mg/dL)* 26 (19–39) 31 (20–51) 33 (22–67) 31 (21–58) 36 (22–98)
GPT (mg/dL)* 22 (14–33) 22 (12–41) 22 (14–43) 23 (14–48) 28 (15–65)
Alkaline phosphatase (mg/dL)* 76 (63–99) 83 (63–106) 82 (64–112) 85 (65–118) 84 (66–122)
APACHE ІІ score 13.4 ± 6.51 16.7 ± 7.33 20.7 ± 7.80 20.3 ± 7.86 22.1 ± 8.51
LOS in hospital (days)* 16 (9–35) 21 (11–38) 22 (11–51) 29 (14–54) 13 (7–28)
  1. *Data are expressed as the median (interquartile range).
  2. Duration of acute kidney injury: 1st tertile, 1–2 days; 2nd tertile, 3–5 days; 3rd tertile, ≥ 6 days.
  3. AKI Acute kidney injury, RRT Renal replacement therapy, CKD Chronic kidney disease, MV Mechanical ventilation, SBP Systolic blood pressure, DBP Diastolic blood pressure, APACHE Acute Physiology and Chronic Health Evaluation, LOS Length of stay.