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Table 3 The study outcomes in patients randomized to placebo or rHuEPO group

From: Prophylaxis with erythropoietin versus placebo reduces acute kidney injury and neutrophil gelatinase-associated lipocalin in patients undergoing cardiac surgery: a randomized, double-blind controlled trial

 

Placebo group (n = 50)

rHuEPO group (n = 50)

p value

Incidence of AKI n (%)

19 (38)

7 (14)

<0.01

  eGFR > 60 mL/min/1.73 m2

6/24 (25)

1/19 (5.26)

0.11

  eGFR < 60 mL/min/1.73 m2

13/26 (50)

6/31 (19.35)

<0.05

Postoperative complication:

 

Bleeding n (%)

2 (4)

1 (2)

0.56

Infection n (%)

4 (8)

2 (4)

0.41

Stroke n (%)

1 (2)

0 (0)

0.32

Cardiac arrhythmia n (%)

7 (14)

6 (12)

0.77

Myocardial infarction n (%)

1 (2)

0 (0)

0.32

Hemodialysis n (%)

2 (4)

0 (0)

0.16

Hospital stay and mortality

 

ICU stay (days)

7 ± 4

4 ± 1

<0.01

Hospital stay (days)

17 ± 9

11 ± 2

<0.01

Hospital deaths n (%)

2 (4)

0 (0)

0.16

  1. eGFR indicates estimated glomerular filtration rate.
  2. ICU indicates intensive care unit.