Table 1 Baseline demographics and laboratory data of all patients and classification according to renal function
From: Mineral metabolism and outcomes in chronic kidney disease stage 2–4 patients
eGFR (mL/min/1.73m2) | ||||||
|---|---|---|---|---|---|---|
Parameters | All Patients (n=466) | >=60 (n=67) | 45-59 (n=123) | 30-44 (n=161) | <=29 (n=115) | P-value a |
Age (yrs) | 65±13.2 | 61.2±15.1 | 62.6±13.7 | 66.1±12.3 | 68±11.6 | <0.001 |
Male Sex (n/%) | 261 (56) | 60 (89.6) | 90 (73.2) | 75 (46.6) | 36 (31.3) | <0.001 |
BMI (kg/m2) | 25.4±4.7 | 25±3.9 | 26.6±5.2 | 25±4.5 | 24.9±4.6 | 0.16 |
Hypertension (n/%) | 422 (90.6) | 58 (86.6) | 115 (93.5) | 147 (91.3) | 102 (88.7) | 0.948 |
Dyslipidemia (n/%) | 324 (69.5) | 49 (73.1) | 85 (69.1) | 114 (70.8) | 76 (66.1) | 0.404 |
DM (n/%) | 263 (56.4) | 28 (41.8) | 65 (52.8) | 102 (63.4) | 68 (59.1) | 0.011 |
CVD (n/%) | 104 (22.3) | 9 (13.4) | 25 (20.3) | 42 (26.1) | 28 (24.3) | 0.967 |
Calcium intake (n/%) | 133 (28.5) | 10 (14.9) | 22 (17.9) | 45 (28) | 56 (48.7) | <0.001 |
Nutritional vitamin D (n/%) | 49 (10.5) | 7 (10.4) | 11 (8.9) | 20 (12.4) | 11 (9.6) | 0.972 |
Active vitamin D (n/%) | 18 (3.9) | 0 (0) | 1 (0.8) | 4 (2.5) | 13 (11.3) | <0.001 |
Laboratory data | ||||||
Calcium (mg/dL)b | 9.3±0.5 | 9.19±0.53 | 9.27±0.43 | 9.32±0.44 | 9.28±0.55 | 0.195 |
Phosphate (mg/dL) | 3.8±0.6 | 3.45±0.51 | 3.58±0.55 | 3.81±0.56 | 4.12±0.71 | <0.001 |
Alkaline Phosphatase (U/L) | 73.4±28.6 | 65.5±23.6 | 67.8±25 | 78.2±27.9 | 79.2±34.9 | 0.034 |
PTH (pg/mL)c | 66 (43–105) | 40 (29–61) | 58 (38–74) | 70 (48–103) | 117 (71–173) | <0.001 |
25-OH-D (ng/mL) | 22±9.1 | 24.6±9.2 | 22.7±10.3 | 22.1±8.3 | 19.8±8.3 | <0.001 |
Albumin (g/L) | 37.5±5.2 | 38.1±6.6 | 39.2±4.3 | 37.1±5.2 | 36±4.8 | <0.001 |
Cholesterol (mg/dL) | 192±56 | 205±74 | 194±55 | 188±57 | 189±41 | 0.301 |
BUN (mg/dL) | 29.7±14.6 | 16.1±4.7 | 22.4±6.8 | 29.6±9.7 | 45.1±16.2 | <0.001 |
Creatinine (mg/dL) | 2.25±1.21 | 1.23±0.16 | 1.62±0.34 | 2.12±0.49 | 3.68±1.53 | <0.001 |
eGFR (mL/min/1.73 m2) | 42.3±16.4 | 70.2±9.6 | 51.9±4.4 | 37.1±4.1 | 22.1±5.2 | <0.001 |
UPCR (mg/g)c,d | 0.67 (0.21-2.43) | 0.24 (0.11-0.88) | 0.35 (0.12-1.72) | 0.58 (0.24-1.89) | 1.78 (0.77-3.86) | <0.001 |