Mineral metabolism and outcomes in chronic kidney disease stage 2–4 patients

BMC Nephrology

Table 2 Hazard ratios of ESRD

Parameters	Unadjusted	Model 1^a	Model 2^b
Phosphate^d (mg/dL)
0-3.7	1 (reference)	1 (reference)	1 (reference)
3.7-4.2	2.04 (1.13-3.7)*	1.53 (0.77-3.03)	1.81 (0.86-3.81)
>4.2	4.56 (2.59-8.03)*	2.38 (1.21-4.68)*	1.98 (0.92-4.28)
PTH^e (pg/mL)
1-42	1 (reference)	1 (reference)	1 (reference)
42-65	12.7 (1.65-97.5)*	5.73 (0.7-46.6)	5.66 (0.69-46.2)
65-105	13.2 (1.74-99.9)*	8.6 (1.09-67.7)*	8.77 (1.12-68.8)*
>105	51.4 (7.08-374)*	20.8 (2.75-158)*	16.5 (2.18-125)*
25-OH-D^f (ng/mL)
>30	1 (reference)	1 (reference)	1 (reference)
15-30	1.84 (0.78-4.34)	3.64 (0.86-15.4)	3.33 (0.78-14.1)
<15	4.07 (1.67-9.92)*	6.82 (1.52-30.6)*	5.73 (1.27-26)*

^aadjusted for age, sex, DM, BMI, serum albumin and eGFR (>=45 or <45 mL/min/1.73 m²), ^bModel 1 further adjusted for other mineral parameters in this table. ^dnormal values 2.5-4.6 mg/dL. ^enormal values 15–65 pg/mL, ^fnormal values >=20 ng/mL. *P<0.05.

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