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Table 1 Baseline characteristics of study subjects

From: Diastolic dysfunction is associated with an increased risk of contrast-induced nephropathy: a retrospective cohort study

Variables

All (n = 735)

CIN (n = 64)

No CIN

p

(n = 671)

Age (years)

64.8 ± 10.6

70.8 ± 10.5

64.2 ± 10.5

<0.001

Sex (male)

514 (69.9%)

39 (60.9%)

475 (70.8%)

0.101

BMI (kg/m2)

24.5 ± 3.3

22.7 ± 3.3

24.7 ± 3.3

<0.001

Systolic BP (mmHg)

119.6 ± 15.1

119.5 ± 21.6

119.6 ± 14.4

0.979

Diastolic BP (mmHg)

71.9 ± 9.9

69.0 ± 14.2

72.2 ± 9.3

0.119

Hypertension

475 (64.6%)

52 (81.3%)

423 (63.0%)

0.004

Diabetes mellitus

250 (34.0%)

39 (60.9%)

211 (31.4%)

<0.001

Previous CABG

23 (3.1%)

5 (7.8%)

18 (2.7%)

0.042

Emergency/ urgent procedure

160 (21.8%)

23 (35.9%)

137 (20.4%)

0.004

Interventional strategy

   

0.521

 Ballooning

23 (3.1%)

1 (1.6%)

22 (3.3%)

 

 Ballooning + Stent insertion

614 (83.5%)

52 (81.3%)

562 (83.8%)

 

 Ballooning + Stent insertion + Thrombus suction

98 (13.3%)

11 (17.2%)

87 (13.0%)

 

3-vessel disease

241 (32.8%)

39 (60.9%)

202 (30.1%)

<0.001

Hypotensive event

90 (12.2%)

25 (39.1%)

65 (9.7%)

<0.001

IABP use

32 (4.4%)

16 (25.0%)

16 (2.4%)

<0.001

Total volume of CM (mL)

237.0 ± 74.5

222.8 ± 71.4

238.1 ± 74.7

0.179

Volume of CM per weight (mL/kg)

3.69 ± 1.31

4.09 ± 1.86

3.66 ± 1.25

0.179

N-acetylcysteine

233 (33.5%)

15 (42.9%)

218 (33.0%)

0.230

BUN (mg/dL)

18.0 ± 7.3

24.2 ± 11.2

17.4 ± 6.6

<0.001

Creatinine (mg/dL)

1.08 ± 0.41

1.50 ± 0.75

1.04 ± 0.33

<0.001

eGFR (mL/min/1.73m2)

74.5 ± 20.5

54.5 ± 25.8

76.4 ± 18.9

<0.001

Hemoglobin (g/dL)

13.2 ± 1.8

11.5 ± 2.1

13.3 ± 1.7

<0.001

Albumin (g/dL)

4.31 ± 0.48

3.85 ± 0.61

4.35 ± 0.44

<0.001

hs-CRP (mg/L)

10.18 ± 28.84

34.11 ± 47.95

7.84 ± 24.77

<0.001

Cholesterol (mg/dL)

164.5 ± 43.5

167.5 ± 56.5

164.3 ± 42.2

0.722

Triglyceride (mg/dL)

140.0 ± 82.3

126.0 ± 87.7

141.3 ± 81.7

0.035

Glucose (mg/dL)

124.6 ± 46.3

156.2 ± 71.3

121.6 ± 42.1

<0.001

Ejection fraction (%)

57.5 ± 13.4

48.8 ± 12.8

58.6 ± 12.7

<0.001

E/E'

13.3 ± 5.3

18.2 ± 7.0

12.9 ± 4.9

<0.001

E/A

0.94 ± 0.48

0.95 ± 0.37

0.94 ± 0.49

0.630

Deceleration time (ms)

204.6 ± 50.1

182.5 ± 50.5

206.7 ± 49.7

<0.001

LV mass (g)

213.6 ± 95.7

233.1 ± 56.2

211.9 ± 98.4

0.001

LV mass index (g/m2)

126.3 ± 88.6

144.0 ± 28.9

124.7 ± 91.9

<0.001

LVDd (mm)

50.0 ± 5.0

51.2 ± 5.6

49.9 ± 4.9

0.030

LA volume index (mL/m2)

28.3 ± 9.7

33.4 ± 11.6

27.8 ± 9.4

<0.001

  1. Abbreviations: BMI body mass index; BP blood pressure; BUN blood urea nitrogen; CABG coronary artery bypass graft; CIN contrast-induced nephropathy; CM contrast media; eGFR estimated glomerular filtration rate; hs-CRP high sensitivity C-reactive protein; IABP intra-aortic balloon pump; LA left atrium; LV left ventricle; LVDd left ventricular end-diastolic dimension.