Changes in the histological spectrum of glomerular diseases in the past 16 years in the North-Eastern region of Romania

Table 4 Correlations between histological diagnoses and clinical presentations

	Nephrotic syndrome (%)		Nephritic syndrome (%)		AUA (%)
	Period 1	Period 2	Period 1	Period 2	Period 1	Period 2
Primary GN
MPGN	43.9	31.9	22.2	27.3	8.3	27.3
MesGN(including IgA)	13.2^a	10.2	27.8	13.6	83.3^d	45.5
FSGS	13.1	14.5	5.6^d	27.3	0^d	18.2
MN	15.8^d	39.1	22.2	18.1	8.4	9
MCD	8.8^c	4.3	0	0	0	0
CGN	5.2	0	22.2	13.7	0	0
Total (N)	114	69	18	22	12	11
Secondary GN
Immune-mediated	41.1	41	11.1^d	54.4	50	50
Dysgammaglobulinaemia associated GN	21.6	20.5	0	18.2	50^d	0
Infectious disease associated GN	33.3	33.4^c	88.9^d	27.3	0^b	50
Others (metabolic, hereditary, etc.)	4	5.1	0	0	0	0
Total (N)	51	39	91	1	2	2

CGN - crescentic glomerulonephritis); FSGS - focal segmental glomerulosclerosis; MCD - minimal change disease; MesGN - mesangioproliferative glomerulonephritis (including IgAN); MN - membranous nephropathy; MPGN - membranoproliferative glomerulonephritis.
^aSignificantly different from nephrotic syndrome and AUA.
^bSignificantly different from nephritic syndrome and AUA.
^cSignificantly different from nephrotic and nephritic syndrome.
^dSignificant differences between the 2 periods studied.

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