From: Proton pump inhibitors and acute kidney injury: a nested case–control study
Variable | Adjusted ORa | 95% CIb | P value |
---|---|---|---|
PPIc use | 1.72 | (1.27-2.32) | < 0.001 |
NSAIDd use | 1.64 | (1.35-2.00) | < 0.001 |
Antibiotic use | 3.66 | (2.86-4.68) | <0.001 |
Diuretic use | 2.28 | (1.78-2.92) | <0.001 |
Diabetes | 2.74 | (2.09-3.60) | < 0.001 |
Hypertension | 1.51 | (1.21-2.89) | < 0.001 |
High cholesterol | 1.10 | (0.89-1.37) | 0.388 |
Myocardial infarction | 0.63 | (0.21-1.89) | 0.409 |
Congestive heart failure | 9.51 | (3.90-23.20) | < 0.001 |
Cerebrovascular disease | 3.65 | (1.28-10.43) | 0.016 |
Peripheral vascular | 4.20 | (1.83-9.66) | < 0.001 |
Paralysis | 1.37 | (0.25-7.34) | 0.717 |
Chronic lung disease | 1.81 | (1.03-3.17) | 0.040 |
Liver disease | 7.38 | (2.88-18.91) | < 0.001 |
Malignancy | 3.72 | (2.07-6.70) | < 0.001 |
Metastatic cancer | 8.86 | (3.35-23.44) | < 0.001 |
Rheumatoid arthritis | 2.62 | (0.97-7.13) | 0.058 |
Osteoarthritis | 0.83 | (0.60-1.21) | 0.373 |