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Table 4 Odds ratios of renal disease from a multiple regression model

From: Proton pump inhibitors and acute kidney injury: a nested case–control study

Variable

Adjusted ORa

95% CIb

P value

PPIc use

1.72

(1.27-2.32)

< 0.001

NSAIDd use

1.64

(1.35-2.00)

< 0.001

Antibiotic use

3.66

(2.86-4.68)

<0.001

Diuretic use

2.28

(1.78-2.92)

<0.001

Diabetes

2.74

(2.09-3.60)

< 0.001

Hypertension

1.51

(1.21-2.89)

< 0.001

High cholesterol

1.10

(0.89-1.37)

0.388

Myocardial infarction

0.63

(0.21-1.89)

0.409

Congestive heart failure

9.51

(3.90-23.20)

< 0.001

Cerebrovascular disease

3.65

(1.28-10.43)

0.016

Peripheral vascular

4.20

(1.83-9.66)

< 0.001

Paralysis

1.37

(0.25-7.34)

0.717

Chronic lung disease

1.81

(1.03-3.17)

0.040

Liver disease

7.38

(2.88-18.91)

< 0.001

Malignancy

3.72

(2.07-6.70)

< 0.001

Metastatic cancer

8.86

(3.35-23.44)

< 0.001

Rheumatoid arthritis

2.62

(0.97-7.13)

0.058

Osteoarthritis

0.83

(0.60-1.21)

0.373

  1. a OR odds ratio.
  2. b CI confidence interval.
  3. c PPI proton pump inhibitor.
  4. d NSAID nonsteroidal anti-inflammatory drugs.