Table 1 Clinical characteristics of the study population by HbA1c tertiles and known diabetes
From: Association of HbA1c and cardiovascular and renal disease in an adult Mediterranean population
HbA1c tertiles | ||||
|---|---|---|---|---|
22-34 mmol/mol | 36-39 mmol/mol | 40-46 mmol/mol | ||
(4.2-5.3%) | (5.4-5.7%) | (5.8-6.4%) | Known diabetes | |
N = 807 | N = 762 | N = 500 | N = 201 | |
Age, y. | 36 ± 12 | 42.4 ± 14.5 | 51 ± 15 | 61 ± 12 |
Male gender, n (%) | 375 (46.5) | 390 (51) | 364 (52.6) | 103 (51) |
Body mass index, kg/m 2 | 25.4 ± 4 | 26.6 ± 5 | 28.3 ± 5 | 30.4 ± 5 |
Systolic blood pressure, mmHg | 121 ± 15 | 125 ± 16 | 128 ± 16 | 134 ± 18 |
Diastolic blood pressure, mmHg | 72 ± 9 | 75 ± 10.4 | 77 ± 10 | 77 ± 10 |
Serum creatinine, μmol/l | 68 ± 17.5 | 69.8 ± 17.5 | 70.7 ± 17.5 | 74.3 ± 25 |
CKD-EPI, ml/min/1.73 m 2 | 109 ± 17 | 104 ± 18 | 98.5 ± 18 | 86 ± 19 |
FPG, mmol/mol | 4.7 ± 0.5 | 4.9 ± 0.5 | 5.2 ± 0.6 | 8.1 ± 0.4 |
HbA1c, mmol/mol (%) | 32 (5.1 ± 0.16) | 36 (5.5 ± 0.11) | 41 (5.9 ± 0.17) | 56 (7.3 ± 1.4) |
Total cholesterol, mmol/l | 3.6 ± 2 | 5.2 ± 1.1 | 5.4 ± 1 | 5.5 ± 1.1 |
LDL-cholesterol, mmol/l | 3 ± 0.8 | 3.3 ± 0.9 | 3.5 ± 0.9 | 3.5 ± 0.9 |
Triglycerides, mmol/l | 1 ± 0.6 | 1.2 ± 0.8 | 1.3 ± 0.9 | 1.7 ± 1 |
Uric acid, mmol/l | 261.7 ± 77.4 | 279.6 ± 83.3 | 291.5 ± 77.3 | 309.3 ± 97.5 |
Urinary albumin/creatinine, mg/mmol | 10.5 ± 49.7 | 9.8 ± 36.2 | 11.3 ± 21.5 | 24.8 ± 63.3 |
Dyslipidemia, n (%) | 51 (6.3) | 96 (12.6) | 98 (20) | 72 (36) |
Hypertension, n (%) | 66 (8.2) | 110 (14.4) | 123 (24.6) | 104 (52) |
Smoking, n (%) | 227 (28) | 222 (29) | 133 (26.6) | 46 (23) |
Cardiovascular disease, n (%) | 13 (1.6) | 17 (2.2) | 33 (6.6) | 31 (15.4) |
CKD, n (%) | 33 (4.1) | 47 (6.2) | 60 (12) | 39 (19.4) |