Table 1 Baseline demographics and prevalence of cardiovascular disease according to disease stage, the CKD-ROUTE study (Oct 2010 - Dec 2011)

Age (years old)

68 ± 14

57 ± 17

67 ± 13

71 ± 12

69 ± 14

<0.001

70 [61–77]

61 [46–71]

70 [60–76]

73 [64–78]

70 [61–78]

Male gender

792

57

361

255

119

<0.001

69.6%

60.0%

76.8%

70.1%

56.9%

Self-feeding ability

1118

94

460

360

204

0.744

99.1%

98.9%

99.1%

99.4%

98.6%

BMI (kg/m²)

23.7 ± 4.0

23.0 ± 4.0

23.7 ± 3.7

23.9 ± 4.1

23.8 ± 4.5

0.351

23.3 [21.0 - 25.8]

22.6 [20.6 - 25.4]

23.5 [21.3 - 25.7]

23.4 [21.0 - 26.4]

23.0 [20.9 - 25.6]

BMI ≥ 25 kg/m²

328

20

129

115

64

0.473

32.8%

26.0%

32.0%

35.1%

33.2%

Diabetes

422

15

141

163

103

<0.001

37.1%

15.8%

30.0%

44.8%

49.3%

HbA1c (NGSP) (%)

6.1 ± 1.0

6.0 ± 1.1

6.1 ± 1.0

6.2 ± 1.0

6.1 ± 1.0

0.083

5.9 [5.6 - 6.5]

5.7 [5.5 - 6.1]

5.9 [5.6 - 6.4]

6.0 [5.6 - 6.6]

5.9 [5.5 - 6.5]

Albumin (g/dl)

4.0 ± 0.8

4.0 ± 0.6

3.8 ± 0.6

3.5 ± 0.6

3.8 ± 0.6

<0.001

4.3 [3.7 - 4.5]

4.1 [3.8 - 4.4]

3.9 [3.5 - 4.2]

3.6 [3.2 - 4.0]

4.0 [3.5 - 4.3]

eGFR (ml/min per 1.73 m²)

32.7 ± 18.7

72.1 ± 8.5

43.3 ± 8.2

22.0 ± 4.4

9.9 ± 3.0

<0.001

29.8 [17.5 - 45.0]

70.6 [64.9 - 79.7]

43.2 [35.5 - 50.2]

21.7 [17.9 - 25.6]

9.8 [7.4 - 12.4]

SBP (mmHg)

140 ± 22

139 ± 20

137 ± 22

140 ± 24

146 ± 22

<0.001

138 [125–152]

136 [125–150]

135 [122–150]

136 [125–154]

143 [136–160]

DBP (mmHg)

78 ± 15

83 ± 14

79 ± 15

75 ± 15

79 ± 15

<0.001

78 [68–87]

83 [74–92]

79 [70–87]

75 [64–83]

78 [69–90]

Diabetic nephropathy

287

10

74

116

87

<0.001

25.5%

10.5%

16.0%

32.0%

42.2%

Nephrosclerosis

451

23

214

159

55

40.0%

24.2%

46.2%

43.8%

26.7%

Glomerulonephritis

216

43

83

49

41

19.2%

45.3%

17.9%

13.5%

19.9%

Others

173

19

92

39

23

15.4%

20.0%

19.9%

10.7%

11.2%

Prevalence of CVD

305

7

104

130

64

<0.001

26.8%

7.4%

22.1%

35.7%

30.6%