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Table 3 Intra- and inter-observer reproducibility of echocardiographic measurements

From: Low agreement between cardiologists diagnosing left ventricular hypertrophy in children with end-stage renal disease

Intra-observer

 

Observer 1

Observer 2

Observer 3

IVSd (mm)

Median (range)

7.0 (3.8-11.0)

6.1 (3.8-10.5)

6.9 (3.7-12.8)

 

Mean diff. [95% CI]

0.2 [0.0-0.4]

0.1 [0.0-0.3]

0.1 [-0.1-0.3]

 

LoA

-1.6-1.9

-1.4-1.7

-1.6-1.8

 

SDC

1.7

1.6

1.7

LVPWd (mm)

Median (range)

7.0 (4.2-12.0)

5.9 (3.4-10.7)

7.9 (4.1-14.2)

 

Mean diff. [95% CI]

0.4 [-0.1-0.7]

0.3 [-0.3-0.8]

0.1 [-0.1-0.4]

 

LoA

-2.1 - 2.9

-1.1-1.7

-2.0 -2.1

 

SDC

2.5

2.0

2.6

LVEDd (mm)

Median (range)

41 (21–59)

44 (23–63)

41 (20–57)

 

Mean diff. [95% CI]

0.9 [0.2-3.2]

0.2 [-0.8-0.5]

0.2 [-0.3-0.6]

 

LoA

-6.1 - 7.9

-2.7- 3.1

-4.3 - 4.4

 

SDC

6.9

2.8

4.4

LVMI

Median (range)

76 (34–219)

70 (39–181)

80 (31–255)

(g/m2)

Mean diff. [95% CI]

1.1 [-2.1-4.3]

0.7 [-1.2-2.5]

0.7 [-1.5-2.9]

 

LoA

- 30.1 – 32.3

-17.4 – 18.8

-20.5 – 21.9

 

SDC

30.5

17.7

20.7

LVHWT

Kappa [95% CI]

0.4 [0.2-0.7]

1.0 [1.0-1.0]

0.4 [0.2-0.6]

LVHMI

Kappa [95% CI]

0.6 [0.4-0.8]

0.6 [0.3-0.9]

0.5 [0.3-0.7]

Inter-observer

 

Observer 1 vs 2

Observer 1 vs 3

Observer 2 vs 3

IVSd (mm)

Mean diff. [95% CI]

1.0 [0.7-1.2]

0.1 [0.0-0.3]

1.1 [0.9-1.3]

 

LoA

1.3 – 3.3

-1.6 - 1.8

-1.1 – 3.3

 

SDC (3 observers)

2.6

LVPWd (mm)

Mean diff. [95% CI]

1.0 [0.8-1.2]

0.6 [0.4-0.8]

1.6 [1.3-1.8]

 

LoA

-1.0 – 3.0

-1.4 – 2.4

-0.8 – 3.9

 

SDC (3 observers)

2.9

LVEDd (mm)

Mean diff. [95% CI]

2.4 [1.9-2.9]

0.3 [-0.4-1.0]

2.7 [2.0-3.4]

 

LoA

-2.1 – 6.9

- 6.4 - 7.2

- 3.8 – 9.3

 

SDC (3 observers)

5.9

LVMI (g/ m2 )

Mean diff. [95% CI]

6.5 [3.9-9.2]

4.0 [1.6-6.4]

10.6 [7.8-13.3]

 

LoA

-6.2 – 31.9

-19.1 – 27.2

- 15.7 – 37.2

 

SDC (3 observers)

24.6

LVHWT

Kappa [95% CI]

0.1 [-0.2-0.5]

0.4 [0.2-0.6]

0.1 [-0.2-0.4]

LVHMI

Kappa [95% CI]

0.3 [0.1-0.5]

0.5 [0.3-0.7]

0.4 [0.2-0.7]

  1. Part 1 (n=92).
  2. IVSd diastolic interventricular septum, LVEDd left ventricular end-diastolic diameter, LVPWd diastolic left ventricular posterior wall thickness, LVMI left ventricular mass index, Mean diff, mean difference, CI confidence interval, LoA limits of agreement, SDC smallest detectable change, LVHWT was defined as a Z-score of IVSd and\or LVPWd > + 2 (according to normal values of healthy Dutch children), LVHMI was defined as LV mass index (g/m2) > 103 g/m2 for boys and > 84 g/m2 for girls.
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BMC Nephrology

ISSN: 1471-2369

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