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Table 2 Cross-sectional associations between anthropometric/ blood parameters and eGFR and ACR 1 by sex

From: Body mass index and metabolic factors predict glomerular filtration rate and albuminuria over 20 years in a high-risk population

 

eGFR

ACR

 

Beta (95% CI)

Beta (95% CI)1

 

Women

Total N

115

114

WHR*10

* -3.89 (−7.37, −0.41)

−0.01 (−0.31, 0.29)

BMI [kg/m2]

0.19 (−0.22, 0.60)

−0.00 (−0.04, 0.03)

Total cholesterol [mmol/l]

−1.46 (−3.87, 0.95)

* -0.23 (−0.43, −0.03)

LDL cholesterol [mmol/l]

−0.70 (−4.09, 2.68)

* -0.31 (−0.59, −0.03)

HDL cholesterol [mmol/l]

−5.17 (−12.45, 2.11)

−0.51 (−1.13, 0.10)

Log(Triglycerides) [mmol/l]

2.92 (−2.95, 8.80)

* 0.60 (0.12, 1.08)

Log(Gamma-GT) [units/l]

−2.14 (−5.24, 0.96)

0.13 (−0.14, 0.41)

Log(CRP) [mg/dl]

−0.70 (−3.51, 2.10)

−0.15 (−0.39, 0.08)

 

Men

Total N

118

118

WHR*10

−0.56 (−3.93, 2.81)

0.27 (−0.14, 0.68)

BMI [kg/m2]

* -0.69 (−1.30, −0.08)

* 0.06 (0.00, 0.13)

Total cholesterol [mmol/l]

0.85 (−1.35, 3.04)

−0.11 (−0.38, 0.16)

LDL cholesterol [mmol/l]

1.10 (−2.02, 4.21)

−0.29 (−0.67, 0.09)

HDL cholesterol [mmol/l]

5.42 (−2.57, 13.42)

−0.31 (−1.31, 0.69)

Log(Triglycerides) [mmol/l]

−2.92 (−7.31, 1.47)

0.23 (−0.32, 0.77)

Log(Gamma-GT) [units/l]

−0.96 (−4.21, 2.28)

0.07 (−0.34, 0.47)

Log(CRP) [mg/dl]

* -2.69 (−5.31, -0.07)

0.20 (−0.12, 0.53)

  1. Models are adjusted for age.
  2. * Significant on alpha < = 0.05.
  3. 1 ACR log-transformed; one percent change (in the independent variable) would yield a percentage change in ACR in models where the independent variable is log-transformed.