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Table 5 Association of sum score of pathologic values for BMI, systolic blood pressure, glucose, cholesterol, triglycerides and GGT with eGFR and ACR 1

From: Body mass index and metabolic factors predict glomerular filtration rate and albuminuria over 20 years in a high-risk population

 

>20 years ago

10 to 20 years ago

5 to 10 years ago

overall

 

Sum score of pathologic values, median (Q1, Q3)

Women

1 (1, 2)

2 (1, 3)

2 (1, 3)

2.00 (1.33, 2.33)

Men

2.5 (1, 3)

2 (1, 3)

2 (1, 3)

2.33 (1.33, 3.33)

 

Change in eGFR (95%CI) for one additional pathologic value

Women

3.01 (−1.28, 7.28)

0.83 (−3.84, 5.49)

1.44 (−2.39, 5.26)

2.75 (−2.51, 8.00)

Men

−1.99 (−3.66, −0.31)

−1.27 (−3.17, 0.64)

−2.81 (−4.59, −1.03)

−2.62 (−4.62, −0.61)

Sex interaction, p-value

0.009

0.241

0.020

0.016

 

Change in log(ACR) (95%CI) 1 )for one additional pathologic value

Women

0.11 (−0.11, 0.33)

0.11 (−0.13, 0.34)

0.01 (−0.19, 0.20)

0.10 (−0.16, 0.37)

Men

0.29 (0.03, 0.55)

0.36 (0.09, 0.64)

0.37 (0.08, 0.65)

0.44 (0.14, 0.74)

Sex interaction, p-value

0.316

0.161

0.041

0.101

  1. Models are adjusted for age.
  2. 1 ACR log-transformed; one additional pathological variable would yield a (100*β) percentage change in ACR.