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Table 4 Association between hypophosphatemia and selected biochemical, socio-demographic and health history variables

From: Hyperphosphatemia is associated with anemia in adults without chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES): 2005–2010

 

Phosphorus >2.5 mg/dL

Phosphorus ≤ 2.5 mg/dL

P Value

Variable

Means±SE or %

Means±SE or %

 

Biochemical

   

Albumin (g/dL)

4.18±0.02

4.26±0.007

<0.01

BUN (mg/dL)

12.69±0.41

11.48±0.30

0.02

BUN≥20 (mg/dL)

2.26

8.46

0.02

Vitamin D (25-0H-D) (ng/mL)

21.10±1.34

22.82±0.60

0.13

Vitamin D (25-OH-D) <10 ng/mL

11.16

5.60

0.14

Vitamin D (25-OH-D) >30 ng/mL

12.21

16.73

0.44

Corrected calcium (mg/dL)

9.44±0.01

9.33±0.03

<0.01

Calcium>10 (mg/dL)

4.32

3.99

0.82

Parathyroid pg/mL

44.02±1.65

54.09+±4.74

0.07

Cholesterol (mg/dL)

194.95±1.91

191.37±3.24

0.35

Creatinine (mg/dL)

0.86±0.01

0.89±0.01

0.10

Uric Acid (mg/dL)

5.45±0.0.08

5.71±0.10

0.02

Hemoglobin A1c

5.62±0.10

5.54±0.03

0.42

Fasting glucose (g/mL)

109.26±3.83

103.88±0.52

0.17

eGFR(MDRD)

92.35±0.73

91.58±1.57

0.69

eGFR (CKD-Epi)

96.25±0.96

95.88±1.83

0.86

C-Reactive Protein (mg/dL)

0.37±0.01

0.61±.16

0.15

Anemia and Iron

   

Low Hemoglobin*

4.18

5.06

0.59

Low Hematocrit^

1.03

1.14

0.63

Low Hemoglobin

1.05

1.17

0.67

Or Hematocrit

   

High Trans Sat>4.6 ng/dL

12.27

14.35

0.71

Low Ferritin <12 g/L

1.85

12.2

<0.01

Sociodemographic

   

Gender

   

 Male

97.44

2.56

0.01

 Female

98.60

1.40

 

Age (Years)

44.23±1.01

45.93±065

0.16

Ethnicity

   

 Mexican

2.07

97.93

0.58

 Other Hisp

1.94

98.06

 

 White

1.91

98.09

 

 Black

2.07

97.93

 

 Other Race

2.82

97.18

 

PIR

2.87±0.13

3.08±0.05

0.14

PIR<1 (poverty)

12.60

13.05

0.83

Health History

   

BMI (kg/m2)

30.01±0.49

28.74±0.25

<0.01

Obese

42.19

36.05

0.06

Diabetes

   

 Yes

1.41

98.59

0.53

 No

2.01

97.99

 

Phosphorus Intake (mg)

1412.27±57.59

1363.72±23.20

0.35

Steroid Use

   

(>last 30 days)

0.86

0.43

0.34

Environmental Phenols

   

Urinary

   

Benzopheone-3 (ng/mL)

   

 ≤6

98.44

1.56

0.18

 >6 & ≤30.1

97.19

2.81

 

 >30.1

96.70

3.30

 

Urinary Bisphenol A (ng/mL)

   

 <1.3

97.91

2.09

0.61

 ≥1.3 & <3

97.02

2.98

 

 ≥3

97.04

2.96

 

Urinary Tricolsan (ng/mL)

   

 ≤4.2

96.32

3.68

0.18

 >4.2 & <23.3

97.68

2.32

 

 ≥23.3

97.97

2.03

 
  1. *Low hemoglobin is defined as <12 g/dL for women and <13 g/dL for men.
  2. ^ Low hematocrit was defined as <36% for women and <41% for men.