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Table 3 Overall performance of different methods used to estimate glomerular filtration rate in patients with different stages of CKD

From: Estimation of glomerular filtration rate by a radial basis function neural network in patients with type-2 diabetes mellitus

 

Median difference of eGFR and sGFR2

Median absolute difference of eGFR

and sGFR2

15% (P15)

30% (P30)

50% (P50)

Total (n = 207)

     

  eGFR4 and sGFR1

-2.83 (-11.23 , 12.13)

32.54 (15.74 , 58.97)

49 (23.7%)

92 (44.4%)

140 (67.6%)

  eGFR6 and sGFR1

-4.06 (-12.59 , 11.21)†

32.78 (16.43 , 57.38)

49 (23.7%)

91 (44.0%)

139 (67.1%)

  eGFRRBF and sGFR

9.76 (-0.19 , 18.02)†‡

26.24 (13.29 , 55.82)

62 (30.0%)

112 (54.1%)

149 (72.0%)

Stage I/II (n = 64)

     

  eGFR4 and sGFR1

9.23 (-9.20 , 37.35)

26.41 (12.20 , 49.65)

19 (29.7%)

35 (54.7%)

49 (76.6%)

  eGFR6 and sGFR1

4.13 (-14.66 , 32.62)†

27.28 (12.73 , 44.42)

16 (25.0%)

33 (51.6%)

49 (76.6%)

  eGFRRBF and sGFR

12.03 (-4.98 , 27.83)

19.73 (12.98 , 35.56)†

21 (32.8%)

43 (67.2%)

56 (87.5%)†

Stage III (n = 81)

     

  eGFR4 and sGFR1

-1.04 (-12.85 , 9.92)

27.01 (13.76 , 58.47)

22 (27.2%)

43 (53.1%)

59 (72.8%)

  eGFR6 and sGFR1

-4.80 (-14.07 , 8.97)†

29.82 (13.65 , 57.57)

25 (30.9%)

41 (50.6%)

58 (71.6%)

  eGFRRBF and sGFR

7.96 (-1.22 , 21.47)†‡

25.40 (11.23 , 48.50)

26 (32.1%)

47 (58.0%)

61 (75.3%)

Stage IV/V (n = 62)

     

  eGFR4 and sGFR1

-6.48 (-11.06 , -0.21)

46.90 (30.81 , 64.90)

8 (12.9%)

14 (22.6%)

32 (51.6%)

  eGFR6 and sGFR1

-6.99 (-11.23 , -1.63)

46.49 (26.56 , 65.17)

8 (12.9%)

17 (27.4%)

32 (51.6%)

  eGFRRBF and sGFR

8.89 (1.95 , 15.48)†‡

49.20 (14.98 , 89.37)

15 (24.2%)

22 (35.5%)

32 (51.6%)

  1. 1 Abbreviations as in Table 2.
  2. 2 Data are given as median difference (IQRs) and median absolute difference (IQRs) between eGFR and three types of eGFR. Within-group comparisons between the measurements were performed using the Wilcoxon Signed Ranks Test for a given CKD stage.
  3. 3 The accuracy of eGFR was expressed as n (%) of measurements within 15% (P15), 30% (P30), and 50% (P50) of sGFR. Data within-measurements were compared using the McNemar test for a given CKD stage.
  4. * p < 0.05, indicates significant difference among CKD stages.
  5. †,‡, P < 0.0167 (0.05/3), indicates significant difference with eGFR4 and sGFR and eGFR6 and sGFR, respectively.