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Table 1 Descriptive analysis of clinical and laboratory data

From: Pulmonary function and exercise tolerance are related to disease severity in pre-dialytic patients with chronic kidney disease: a cross-sectional study

Variables

Control

Stage 3

Stage 4

Stage 5

P

 

(CG = 9)

(G3 = 10)

(G$ = 10)

(G5 = 9)

 

Age (years)

51.5 ± 7.5

56.8 ± 5.8

52.3 ± 8.5

56.3 ± 9.0

0.351

Sex (F/M)

4/5

5/5

6/4

5/4

0.914

BMI (kg/m2)

27.2 ±4.6

29.5 ± 5.7

26.3 ± 6.5

27.9 ± 5.6

0.655

CKD Etiology:

     

Hypertensive Nx

-

5

3

2

<0.001*

Diabetic Nx

-

1

2

2

 

CGN

-

1

2

3

 

Others

-

3

3

2

 

Comorbidities:

     

H

-

10

9

9

<0.001*

DM

-

2

4

2

<0.001*

Dyslipidemia

-

6

6

8

<0.001*

eGFR (mL/min/1.73m2)

77.6 ± 9.8b,c,d

43.8 ± 8.7a,c,d

21.3 ± 4.2a,b,d

12.7 ± 3.7a,b,c

<0.001*

Creatinine (mg/dL)

0.9 ± 0.1b,c,d

1.5 ± 0.2a,c,d

2.7 ± 0.6a,b,d

4.4 ± 1.3a,b,c

<0.001*

Potassium (meq/L)

4.6 ± 0.4d

4.4 ± 0.5d

4.7 ± 0.9

5.4 ± 0.9

0.049

Calcium (mg/dL)

10.0 ± 0.6

9.9 ± 1.0

9.9 ± 0.7

10.2 ± 0.6

0.852

Phosphorus (mg/dL)

4.8 ± 2.2

3.6 ± 0.6

4.1 ± 0.8

4.9 ± 0.6

0.081

Alkaline phosphatase (U/L)

155.2 ± 41.1d

193.8 ± 38.3d

220.1 ± 51.1d

305.5 ± 144.7

0.014

PTHi (pg/mL)

71.2 ± 29.8d

77.0 ± 24.9d

114.2 ± 52.2d

337.2 ± 283.0

0.004

Hemoglobin (g/dL)

15.0 ± 1.8c,d

13.7 ± 1.4c

12.3 ± 1.3

12.3 ± 1.6

0.003

Albumin (g/dL)

3.9 ± 0.1

4.2 ± 0.3

3.6 ± 0.5

4.2 ± 0.5

0.102

Total cholesterol (mg/dL)

201.6 ± 41.5

207.8 ± 43.5

190.6 ± 40.7

215.4 ± 59.3

0.698

Triglycerides (mg/dL)

106.5 ± 45.9

147.6 ± 81.8

179.1 ± 120.0

252.1 ± 221.3

0.163

HCO3 (mmol/L)

28.0 ± 0.8c,d

27.3 ± 2.5c,d

23.7 ± 3.8

22.0 ± 4.5

0.003

  1. <0.001* = P-value for comparison between the control Group and the CKD groups (Stage 3,4 and 5); BMI Body Mass Index, Nx Nephropathy, CKD Chronic kidney disease, CGN Chronic glomerulonephritis, H Hypertension, DM Diabetes Mellitus, eGFR estimated Glomerular Filtration Rate, PTHi Parathyriod Hormone Intact Molecule, HCO 3 Bicarbonate.
  2. Post hoe analysis: a = differs from CG at p<0.05; c = differs from G4 at p<0.05; d = differs from G5 at p<0.05.