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Table 1 Descriptive analysis of clinical and laboratory data

From: Pulmonary function and exercise tolerance are related to disease severity in pre-dialytic patients with chronic kidney disease: a cross-sectional study

Variables Control Stage 3 Stage 4 Stage 5 P
  (CG = 9) (G3 = 10) (G$ = 10) (G5 = 9)  
Age (years) 51.5 ± 7.5 56.8 ± 5.8 52.3 ± 8.5 56.3 ± 9.0 0.351
Sex (F/M) 4/5 5/5 6/4 5/4 0.914
BMI (kg/m2) 27.2 ±4.6 29.5 ± 5.7 26.3 ± 6.5 27.9 ± 5.6 0.655
CKD Etiology:      
Hypertensive Nx - 5 3 2 <0.001*
Diabetic Nx - 1 2 2  
CGN - 1 2 3  
Others - 3 3 2  
Comorbidities:      
H - 10 9 9 <0.001*
DM - 2 4 2 <0.001*
Dyslipidemia - 6 6 8 <0.001*
eGFR (mL/min/1.73m2) 77.6 ± 9.8b,c,d 43.8 ± 8.7a,c,d 21.3 ± 4.2a,b,d 12.7 ± 3.7a,b,c <0.001*
Creatinine (mg/dL) 0.9 ± 0.1b,c,d 1.5 ± 0.2a,c,d 2.7 ± 0.6a,b,d 4.4 ± 1.3a,b,c <0.001*
Potassium (meq/L) 4.6 ± 0.4d 4.4 ± 0.5d 4.7 ± 0.9 5.4 ± 0.9 0.049
Calcium (mg/dL) 10.0 ± 0.6 9.9 ± 1.0 9.9 ± 0.7 10.2 ± 0.6 0.852
Phosphorus (mg/dL) 4.8 ± 2.2 3.6 ± 0.6 4.1 ± 0.8 4.9 ± 0.6 0.081
Alkaline phosphatase (U/L) 155.2 ± 41.1d 193.8 ± 38.3d 220.1 ± 51.1d 305.5 ± 144.7 0.014
PTHi (pg/mL) 71.2 ± 29.8d 77.0 ± 24.9d 114.2 ± 52.2d 337.2 ± 283.0 0.004
Hemoglobin (g/dL) 15.0 ± 1.8c,d 13.7 ± 1.4c 12.3 ± 1.3 12.3 ± 1.6 0.003
Albumin (g/dL) 3.9 ± 0.1 4.2 ± 0.3 3.6 ± 0.5 4.2 ± 0.5 0.102
Total cholesterol (mg/dL) 201.6 ± 41.5 207.8 ± 43.5 190.6 ± 40.7 215.4 ± 59.3 0.698
Triglycerides (mg/dL) 106.5 ± 45.9 147.6 ± 81.8 179.1 ± 120.0 252.1 ± 221.3 0.163
HCO3 (mmol/L) 28.0 ± 0.8c,d 27.3 ± 2.5c,d 23.7 ± 3.8 22.0 ± 4.5 0.003
  1. <0.001* = P-value for comparison between the control Group and the CKD groups (Stage 3,4 and 5); BMI Body Mass Index, Nx Nephropathy, CKD Chronic kidney disease, CGN Chronic glomerulonephritis, H Hypertension, DM Diabetes Mellitus, eGFR estimated Glomerular Filtration Rate, PTHi Parathyriod Hormone Intact Molecule, HCO 3 Bicarbonate.
  2. Post hoe analysis: a = differs from CG at p<0.05; c = differs from G4 at p<0.05; d = differs from G5 at p<0.05.