|
Variables
|
Exercise group
|
Dopamine agonists group
|
Placebo group
|
|---|
|
Sleep Diary
| | | |
|
Baseline
|
7.69±5.51
|
10.28±2.87
|
8.42±5.09
|
|
6-m post
|
7.30±4.13
|
5.85±3.71†
|
8.85±4.09
|
|
Δ Change
|
−0.71±3.22
|
- 4.42±3.10#¶
|
0.42±2.7
|
|
95% CI of Δ change
|
−2.49 to 1.07
|
−7.28 to −1.56
|
2.91 to −2.07
|
|
Epworth Sleepiness Scale
| | | |
|
Baseline
|
5.15±2.54
|
7.85±5.24
|
8.71±5.37
|
|
6-m post
|
5.15±2.47
|
5.42±1.98
|
8.42±4.92
|
|
Δ Change
|
−0.35±2.73
|
−2.42±5.38
|
- 0.28±4.19
|
|
95% CI of Δ change
|
−1.85 to 1.15
|
−7.39 to 2.55
|
−4.15 to 3.59
|
|
Zung Depression Scale
| | | |
|
Baseline
|
43.45±8.06
|
46.85±13.49
|
37.85±12.15
|
|
6-m post
|
35.84±6.38†#
|
39.42±4.35
|
43.71±11.17†¶
|
|
Δ Change
|
−8.28±7.91#
|
−7.42±10.34#
|
5.85±6.41
|
|
95% CI of Δ change
|
−12.60 to −3.91
|
−16.96 to 2.12
|
11.70 to −0.07
|
|
IRLS score
| | | |
|
Baseline
|
25.14±9.09
|
24.14±5.55
|
19.71±7.49
|
|
6-m post
|
13.42±11.28†
|
11.57±7.84†
|
18.57±10.65
|
|
Δ Change
|
−13.12±8.59#
|
- 12.57±5.31#
|
- 1.14±8.43
|
|
95% CI of Δ change
|
−17.87 to −8.37
|
−17.47 to −7.67
|
−8.93 to 6.65
|
|
SF-36 MCS score
| | | |
|
Baseline
|
61.1±22.0
|
39.1±23.8
|
68.1±19.1
|
|
6-m post
|
70.4±18.7
|
63.0±17.0†
|
65.0±21.9
|
|
Δ Change
|
9.3±26.7
|
23.8±14.1
|
3.1±9.8
|
|
95% CI of Δ change
|
24.1 to 5.4
|
36.9 to 10.7
|
5.9 to −12.2
|
|
SF-36 PCS score
| | | |
|
Baseline
|
64.9±18.6
|
48.7±21.0
|
64.4±22.5
|
|
6-m post
|
76.4±15.6†
|
68.8±19.2†
|
70.5±26.5
|
|
Δ Change
|
11.5±18.4
|
20.1±6.0
|
6.1±5.7
|
|
95% CI of Δ change
|
21.7 to 1.2
|
25.7 to 14.5
|
20.2 to −7.9
|
- All data are mean ± SD. Abbreviations: IRLS International restless legs syndrome severity scale, SF-36 Self reported quality of life questionnaire, MCS Mental component summary, PCS Physical component summary.
- #Significantly different than placebo group.
- ¶Significantly different than exercise group.
-
†Significantly different from the respective baseline value.
