Author | Year | Country | # Participants | Study period | Patient category | Treatment | Comparator | Vitamin D dosage | Study design | Statistical methods | Follow-up duration months | ITT analysis | NOS scale |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Teng et al. | 2003 | United States | 67399 | 1999 to 2001 | Prevalent HD patients | Paricalcitol | Calcitriol | NA | Historical cohort multicenter study | Baseline Cox model; as-treated analysis | 36 | no | 6 |
Shoji et al. | 2004 | Japan | 242 | 1992 to 1998 | Prevalent HD patients | Alfacalcidol | No treatment | NA | Prospective cohort single center study | Baseline Cox model | 76 | no | 9 |
Teng et al. | 2005 | United States | 51037 | 1996 to 1999 | Prevalent HD patients | Calcitriol or paricalcitol | No treatment | NA | Historical cohort multicenter study | Time-dependent Cox model; marginal structural model | 24 | yes | 6 |
Melamed et al. | 2006 | United States | 1007 | 1995 to 1998 | Incident HD and PD patients | Calcitriol | No treatment | NA | Prospective cohort multicenter study | Baseline and time-dependent Cox models | 48 | no | 5 |
Kalantar-Zadeh et al. | 2006 | United States | 58058 | 2001 to 2003 | Prevalent HD patients | Paricalcitol | No treatment | NA | Historical cohort multicenter study | Baseline and time-dependent Cox models | 24 | no | 7 |
Tentori et al. | 2006 | United States | 14967 | 1999 to 2004 | Prevalent HD patients | Calcitriol; paricalcitol; doxercalciferol | No treatment; each other | NA | Historical cohort multicenter study | Baseline and time-dependent Cox models; as treated analysis | 60 | yes | 7 |
Kovesdy et al. | 2008 | United States | 520 | 1990 to 2007 | CKD stage 2 to 4 patients | Calcitriol | No treatment | 1.75-3.5ug/week | Prospective cohort single center study | Baseline Cox model | 48 | no | 6 |
Naves-Diaz et al. | 2008 | Argentina; Brazil; Colombia; Chile; Mexico; Venezuela | 16004 | 2000 to 2004 | Prevalent HD patients | Calcitriol or alfacalcidol | No treatment | NA | Historical cohort multicenter study | Time-dependent Cox model | 54 | yes | 6 |
Shinaberger et al. | 2008 | United States | 34307 | 2001 to 2004 | Prevalent HD patients | Paricalcitol | No treatment | 1.7-30.8ug/week | Historical cohort multicenter study | Baseline Cox model | 30 | no | 7 |
Shoben et al. | 2008 | United States | 1418 | 1999 to 2007 | CKD stage 3 to 4 patients | Calcitriol | No treatment | Â | Historical cohort multicenter study | Baseline Cox model; as-treated analysis | 48 | yes | 8 |
Wolf et al. | 2008 | United States | 9303 | 2004 to 2005 | Incident HD patients | Calcitriol; paricalcitol; doxercalciferol | No treatment; stratified by race | NA | Prospective cohort multicenter study | Baseline Cox model | 12 | no | 5 |
Tentori et al. | 2009 | France; Germany; Italy; Japan; Spain; United Kingdom; United States; Australia; Belgium; Canada; New Zealand; Sweden | 38066 | 1996 to 2009 | Incident HD patients | Calcitriol; paricalcitol; doxercalciferol | No treatment; each other | NA | Prospective cohort multicenter study | Baseline and time-dependent Cox models; Marginal structural model | 30 | no | 5 |
Peter et al. | 2009 | United States | 193830 | 1999 to 2004 | Prevalent and incident HD | Calcitriol; paricalcitol; doxercalciferol | No treatment | 0.25-3.5ug/week* | Historical cohort multicenter study | Time-dependent Cox model | 63 | no | 6 |
Chang et al. | 2009 | Taiwan | 702 | 1993 to 2004 | Incident HD | Calcitriol | No treatment | 0.75-6.0ug/week | Retrospective cohort single center study | Baseline Cox model | 140 | no | 6 |
Konta et al. | 2010 | Japan | 466 | 2003 to 2008 | Incident HD | Calcitriol; falecalcitriol; maxacalcitol | No treatment | 1.1-5.1ug/week; 1.4-2.6ug/week; 2.6-5.4ug/week | Prospective cohort multicenter study | Baseline Cox model | 60 | no | 7 |
Sugiura et al. | 2010 | Japan | 665 | 1992 to 2008 | Incident HD | Alfacalcidol | No treatment | 1.75-3.5ug/week | Retrospective cohort single center study | Baseline Cox model | 132 | no | 6 |
Jean et al. | 2011 | France | 648 | 2005 to 2009 | Prevalent HD patients | Alfacalcidol | No treatment | 1.75-9ug/week | Prospective cohort multicenter study | Baseline Cox model | 42 | no | 5 |
Brancaccio et al. | 2011 | Italy | 2378 | 2006 to 2007 | Incident HD patients | Calcitriol; paricalcitol | No treatment | 1.9-3.3ug/week; 11.2-15.9ug/week | Prospective cohort multicenter study | Time-dependent Cox model | 18 | no | 5 |
Dierkes et al. | 2011 | Germany | 650 | NA | NA | Calcitrol; cholecalciferol | No treatment | NA | Prospective cohort multicenter study | NA | 24 | NA | NA |
Ogawa et al. | 2012 | Japan | 190 | 2005 to 2010 | Prevalent HD patients | Alfacalcidol | No treatment | 3.4-7.0ug/week | Prospective cohort single center study | Baseline Cox model | 60 | no | 9 |