Table 1 Baseline characteristics of HD patients
HD patients | ESA ≤8,000 (units/week) | ESA >8,000 (units/week) | ||
|---|---|---|---|---|
|  | Hb ≥11 (g/dl) | Hb <11 (g/dl) | Hb ≥11 (g/dl) | Hb <11 (g/dl) |
Number | 380 | 264 | 158 | 211 |
Age (years) | 64.5 (13.2) | 64.1 (14.4) | 64.9 (13.7) | 64.2 (12.8) |
Sex (%) men | 60.4 | 56.1 | 65.0 | 56.4 |
Weight (kg) | 70.6 (12.4) | 72.0 (14.3) | 74.1 (14.9) | 73.6 (14.8) |
ESA dose (units/week) | 6,000 (4,000-8,000) | 6,000 (4,000-8,000) | 12,000 (10,000-16,000) | 12,000 (12,000-18,000) |
ERI (units/week/kg/Hb) | 6.5 (2.9) | 7.9 (3.4) | 16.0 (6.3) | 22.3 (13.5) |
Primary kidney disease (%) | Â | Â | Â | Â |
- Diabetes mellitus | 10.6 | 17.4 | 16.5 | 15.6 |
- Glomerulonephritis | 11.1 | 7.6 | 8.2 | 8.5 |
- Renal vascular disease | 22.2 | 21.6 | 12.7 | 19.0 |
- Other | 56.2 | 53.4 | 62.7 | 56.9 |
Comorbidity (%) | Â | Â | Â | Â |
- Diabetes mellitus | 17.1 | 20.8 | 27.2 | 24.2 |
- Malignancy | 7.4 | 9.8 | 11.4 | 18.5 |
- Cardiovascular disease | 39.2 | 41.3 | 32.9 | 40.8 |
Weekly Kt/V urea (Watson) | 3.7 (0.9) | 3.5 (0.9) | 3.7 (0.8) | 3.7 (1.0) |
rGFR (ml/min/1.73Â m2) | 2.9 (1.5-4.4) | 2.3 (0.8-3.8) | 2.1 (0.8-4.2) | 1.5 (0.4-3.2) |
Nutritional status (SGA) (%) | Â | Â | Â | Â |
- Severely malnourished | 0.3 | 2.2 | 0.8 | 5.4 |
- Mild-moderate | 19.1 | 25.4 | 27.1 | 37.3 |
- Well-nourished | 80.6 | 72.4 | 72.0 | 57.2 |
Laboratory values | Â | Â | Â | Â |
- Hemoglobin (g/dl) | 12.1 (11.6-12.7) | 10.3 (9.5-10.6) | 12.1 (11.6-12.8) | 9.8 (9.2-10.5) |
- Albumin (g/l) | 37.5 (4.5) | 36.0 (4.9) | 35.6 (4.5) | 34.1 (6.0) |
- Ferritin (μg/l) | 190 (104–380) | 175 (94–379) | 229 (121–434) | 257 (118–511) |
- PTH (pmol/l) | 12.1 (5.5-23.8) | 10.6 (4.7-23.9) | 16.3 (6.4-33.7) | 10.0 (3.2-23.4) |
- CRP (mg/l) | 6.0 (3.0-12.0) | 6.0 (3.0-15.0) | 9.0 (3.0-17.0) | 14.0 (6.0-34.5) |