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Table 5 Hazard ratios for all-cause mortality by ERI quartile

From: Erythropoiesis-stimulating agent resistance and mortality in hemodialysis and peritoneal dialysis patients

     All-cause mortality  
ERI ESA/kg/Hb ERI quartile Patients (n) Unadjusted HR   Adjusted HR1   Adjusted HR2
HD patients      
  <5.87 1 253 1   1   1
  5.87-9.46 2 253 1.08 (0.82-1.43)   1.16 (0.88-1.55)   1.11 (0.83-1.49)
  9.47-14.28 3 254 1.33 (1.01-1.74)   1.28 (0.97-1.68)   1.07 (0.81-1.43)
  >14.28 4 253 1.81 (1.39-2.36)   1.85 (1.41-2.42)   1.34 (1.00-1.80)
PD patients      
  <3.21 1 115 1   1   1
  3.21-4.81 2 115 0.63 (0.36-1.12)   0.45 (0.25-0.80)   0.45 (0.25-0.83)
  4.82-7.90 3 115 1.24 (0.75-2.03)   0.95 (0.56-1.61)   0.77 (0.43-1.36)
  >7.90 4 116 1.72 (1.07-2.77)   1.46 (0.88-2.41)   1.18 (0.68-2.07)
  1. Values are shown as hazard ratios (95% CI).
  2. Categories are defined by quartiles of ERI (weekly ESA dose/kg/Hb). The highest ERI quartile (quartile 4) corresponds to ESA resistant patients and the lowest ERI quartile (quartile 1) corresponds to good ESA responders.
  3. 1 Adjusted for age, sex, weight, primary kidney disease, diabetes mellitus, malignancy, cardiovascular disease.
  4. 2 Additional adjusted for weekly Kt/V urea, rGFR, nutritional status, albumin, ferritin, PTH and CRP.