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Table 1 Urine output, urine osmolarity (u-osm), free water clearance (C H2O ), urinary AQP2 excretion per minute (u-AQP2), urinary excretion of ENaCγ per minute (u-ENaCγ), urinary sodium excretion (u-Na) and fractional excretion of sodium (FE Na ) during 24-hours urine collection with fluid deprivation (12 PM to 8.00 AM) in a randomised, crossover study of 23 healthy subjects

From: Effect of volume expansion with hypertonic- and isotonic saline and isotonic glucose on sodium and water transport in the principal cells in the kidney

 

Examination day:

P (ANOVA)

0.9% NaCl

3% NaCl

Glucose

Urine Output (ml/24 h)

2306(559)

2120(695)

2281(650)

0.56

u-osm (mosm/24 h)

848(231)

797(207)

833(239)

0.73

C H2O (ml/min)

-0.46(0–61)

-0.47(0.57)

-0.44(0.64)

0.99

u-AQP2 (ng/min)

0.93(0.24)

0.91(0.22)

0.93(0.24)

0.89

u-ENaCγ (pg/min)

405(163)

389(188)

385(164)

0.92

u-Na (mmol/24 h)

124(52)

119(41)

120(56)

0.93

FE Na (%)

0.49(0.15)

0.47(0.13)

0.45(0.18)

0.67

  1. Values are means with SD in brackets. One-way ANOVA was used for comparison between groups.