Table 6 Pre-dialysis mean serum bicarbonate, phosphate, potassium and corrected calcium for separate doses of sevelamer hydrochloride

Bicarbonate

Non SH user*

22.83 (2.93)

ref

22.77 (2.88)

ref

22.85 (2.91)

ref

Low dose

22.16 (2.53)

-0.56 (-1.16 to 0.04)

22.21 (2.53)

-0.16 (-0.63 to 0.32)

22.34 (2.56)

-0.22 (-0.63 to 0.20)

Moderate dose

21.06 (2.68)

-1.66 (-2.18 to -1.13)

21.31 (2.62)

-0.99 (-1.39 to -0.59)

21.61 (2.62)

-0.94 (-1.27 to -0.61)

High dose

20.66 (3.14)

-1.89 (-2.51 to -1.26)

<0.001

20.61 (3.30)

-1.60 (-2.03 to -1.16)

<0.001

21.04 (3.31)

-1.27 (-1.63 to -0.91)

<0.001

Phosphate ^{^}

Non SH user*

1.55 (0.52)

ref

1.57 (0.54)

ref

1.57 (0.55)

ref

Low dose

1.44 (0.43)

-0.07 (-0.17 to 0.03)

1.44 (0.40)

-0.09 (-0.17 to -0.01)

1.43 (0.42)

-0.06 (-0.13 to 0.01)

Moderate dose

1.50 (0.44)

0.03 (-0.06 to 0.12)

1.51 (0.45)

-0.01 (-0.08 to 0.06)

1.49 (0.46)

-0.05 (-0.10 to 0.01)

High dose

1.89 (0.54)

0.14 (0.03 to 0.26)

0.03

1.86 (0.53)

0.08 (0.01 to 0.16)

0.07

1.84 (0.53)

0.04 (-0.02 to 0.10)

0.53

Potassium

Non SH user*

4.85 (0.70)

ref

4.83 (0.70)

ref

4.85 (0.72)

ref

Low dose

4.99 (0.68)

0.07 (-0.07 to 0.22)

4.97 (0.67)

0.09 (-0.03 to 0.20)

4.99 (0.65)

0.07 (-0.03 to 0.17)

Moderate dose

5.14 (0.72)

0.20 (0.07 to 0.33)

5.07 (0.70)

0.16 (0.07 to 0.26)

5.09 (0.69)

0.15 (0.07 to 0.23)

High dose

5.19 (0.72)

0.21 (0.05 to 0.37)

<0.001

5.16 (0.72)

0.21 (0.11 to 0.32)

<0.001

5.14 (0.70)

0.17 (0.09 to 0.26)

<0.001

Corrected Calcium ^{^}

Non SH user*

2.34 (0.19)

ref

2.35 (0.19)

ref

2.36 (0.19)

ref

Low dose

2.35 (0.18)

-0.04 (-0.08 to 0.00)

2.35 (0.18)

-0.03 (-0.06 to 0.00)

2.35 (0.18)

-0.04 (-0.06 to -0.01)

Moderate dose

2.32 (0.20)

-0.03 (-0.07 to 0.00)

2.33 (0.19)

-0.03 (-0.06 to -0.01)

2.35 (0.18)

-0.04 (-0.06 to -0.02)

High dose

2.27 (0.19)

-0.05 (-0.10 to -0.01)

0.02

2.28 (0.18)

-0.05 (-0.08 to -0.02)

<0.001

2.29 (0.18)

-0.04 (-0.07 to -0.02)

<0.001