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Table 2 Adjusted odds ratios for the associations between patient characteristics and non-adherence to phosphate binder use

From: Potentially modifiable factors associated with non-adherence to phosphate binder use in patients on hemodialysis

Patient characteristics

Odds ratios (95%Confidence intervals)

Minimally adjusted

Extensively adjusted

Sociodemographics

Age per each 10 years

0.88 (0.76-1.02)

0.87 (0.73-1.04)

Female vs. male

1.53 (1.03-2.29)

1.48 (0.94-2.33)

Non-white vs. white

1.24 (0.66-2.33)

1.28 (0.67-2.47)

Less than high school vs higher

1.09 (0.71-1.70)

1.15 (0.73-1.82)

Poor/very poor vs. higher economic class

1.20 (0.78-1.84)

1.23 (0.78-1.94)

Married (yes vs. no)

1.09 (0.72-1.64)

1.07 (0.70-1.65)

Living with family (yes vs. no)

0.65 (0.34-1.26)

0.64 (0.32-1.27)

Years on dialysis (each 2 years)

0.91(0.84-0.99)

0.87 (0.80-0.95)

Catheter as vascular access (yes vs. no)

1.87 (0.82-4.28)

2.10 (0.85-5.15)

Comorbid conditions (yes vs. no)

Cerebrovascular disease

2.86 (0.93-8.77)

3.30 (1.03-10.61)

Diabetes

0.69 (0.41-1.18)

0.71 (0.40-1.29)

Heart failure

0.77 (0.41-1.44)

0.84 (0.43-1.65)

Ischemic heart disease

0.99 (0.52-1.93)

1.06 (0.52-2.20)

Peripheral vascular disease

0.82 (0.30-2.26)

0.87 (0.29-2.63)

Physician-diagnosed depression

1.15 (0.47-2.80)

1.17 (0.46-3.01)

Depression score by CES-D* ≥18 vs. lower

0.88 (0.57-1.37)

0.90 (0.57-1.44)

Cancer

1.03 (0.36-2.96)

1.09 (0.37-3.23)

Laboratory variables

PTH (per 300 pg/mL higher)

1.11 (0.99-1.24)

1.14(1.01-1.28)

Serum phosphorus (>3.5 vs. 3.5-5.5 mg/dL)

0.43 (0.19-0.93)

0.50 (0.22-1.13)

Serum phosphorus (>5.5 vs. 3.5-5.5 mg/dL)

0.50 (0.33-0.75)

0.53 (0.34-0.82)

Serum calcium (per 1 mg/dL higher)

0.99 (0.81-1.22)

1.02 (0.82-1.27)

Hemoglobin (>11 vs. ≥11 g/dL)

0.98 (0.67-1.45)

0.94 (0.62-1.41)

Serum albumin (>3.5 vs. ≥3.5 g/dL)

1.48 (0.93-2.35)

1.50 (0.91-2.50)

Serum creatinine (per 1 mg/dL higher)

0.95 (0.89-1.00)

0.97 (0.91-1.04)

  1. CES-D Center for Epidemiological Studies Depression Scale.
  2. Minimally adjusted odds ratios were adjusted for age, sex, race, education, economic class, marital status, living with family, years on dialysis and dialysis by catheter.
  3. Extensively adjusted odds ratios were adjusted for all listed variables.