Table 1 Demographic and clinical data of controls, subjects with prediabetes or diabetes
| Â | Controls (C) | Prediabetes (PD) | Diabetes (D) | p-value |
|---|---|---|---|---|
(n = 15) | (n = 19) | (n = 67) | ||
Age (years) | 40 ± 11 | 61 ±12 | 53 ± 13 | <0.001 |
Gender (female) | 8 (53%) | 15 (79%) | 42 (63%) | 0.267 |
Ethnicity (white) | 86.7% | 94.7% | 73.1% | 0.091 |
BMI (kg/m 2 ) | 25.1 ± 2.4 | 31.6 ± 7.7 | 28.9 ± 6.5 | 0.016 |
SBP (mm Hg) | 116 ± 9 | 128 ±13 | 137 ± 18 | <0.001 |
DBP (mm Hg) | 72 ± 7 | 77 ±10 | 80 ± 8 | 0.006 |
Serum creatinine (mg/dL) | 0.86 ± 0.20 | 0.77 ± 0.10 | 1.55 ± 1.19 | 0.011 |
eGFR (mL/min/1.73 m 2 ) | 98.8 ± 23.1 | 95.7 ± 21.8 | 84.9 ± 39.0 | 0.038 |
Blood glucose (mg/dL) | 90 ± 11 | 105 ± 11 | 162 ± 60 | <0.001 |
Hb1Ac (%) | 5.1 ± 0.6 | 5.8 ± 0.5 | 8.7 ± 1.9 | <0.001 |
Hb1Ac (mmol/mol) | 33 ± 0.6 | 40 ± 0.5 | 72 ± 1.9 | <0.001 |
Albuminuria (mg/g creatinine) | 3.2 (1.5– 6.6) | 9.6 (3.7– 6.6) | 375.0 (12.0–1340.5) | <0.001 |