Figure 2From: Switching hemodialysis patients from sevelamer hydrochloride to bixalomer: a single-center, non-randomized analysis of efficacy and effects on gastrointestinal symptoms and metabolic acidosis Changes of metabolic acidosis. All parameters of metabolic acidosis (A: pH, B: HCO3 -, C: base excess, D: anion gap) improved significantly in the switch group. (*, P < 0.05, **, P < 0.01, paired t tests, compared with before switching). Back to article page